病毒性心肌炎和心包炎中的心律失常

Arrhythmias in viral myocarditis and pericarditis.

作者信息

Baksi A John, Kanaganayagam G Sunthar, Prasad Sanjay K

机构信息

Cardiovascular Biomedical Research Unit, Royal Brompton Hospital & Harefield NHS Foundation Trust and Imperial College London, Sydney Street, London SW3 6NP, UK; Cardiovascular Magnetic Resonance Unit, Royal Brompton Hospital, Sydney Street, London SW3 6NP, UK.

出版信息

Card Electrophysiol Clin. 2015 Jun;7(2):269-81. doi: 10.1016/j.ccep.2015.03.009. Epub 2015 Mar 31.

DOI:10.1016/j.ccep.2015.03.009

PMID:26002391

Abstract

Acute viral myocarditis and acute pericarditis are self-limiting conditions that run a benign course and that may not involve symptoms that lead to medical assessment. However, ventricular arrhythmia is frequent in viral myocarditis. Myocarditis is thought to account for a large proportion of sudden cardiac deaths in young people without prior structural heart disease. Identification of acute myocarditis either with or without pericarditis is therefore important. However, therapeutic interventions are limited and nonspecific. Identifying those at greatest risk of a life-threatening arrhythmia is critical to reducing the mortality. This review summarizes current understanding of this challenging area in which many questions remain.

摘要

急性病毒性心肌炎和急性心包炎是自限性疾病，病程呈良性，可能不会出现促使患者就医评估的症状。然而，室性心律失常在病毒性心肌炎中很常见。心肌炎被认为是导致无结构性心脏病的年轻人心源性猝死的一大原因。因此，识别有无心包炎的急性心肌炎很重要。然而，治疗干预措施有限且缺乏特异性。识别出最有可能发生危及生命心律失常的患者对于降低死亡率至关重要。本综述总结了目前对这一充满挑战领域的认识，其中仍存在许多问题。