Pearce Anna, Marshall Helen, Bedford Helen, Lynch John
Population, Policy and Practice, UCL Institute of Child Health, University College London, London, United Kingdom; School of Population Health, University of Adelaide, South Australia, Australia.
School of Population Health, University of Adelaide, South Australia, Australia; Robinson Research Institute and School of Paediatrics and Reproductive Health, University of Adelaide, South Australia, Australia; Vaccinology and Immunology Research Trials Unit, Women's and Children's Hospital, South Australia, Australia.
Vaccine. 2015 Jun 26;33(29):3377-83. doi: 10.1016/j.vaccine.2015.04.089. Epub 2015 May 21.
To examine barriers to childhood immunisation experienced by parents in Australia.
Cross-sectional analysis of secondary data.
Nationally representative Longitudinal Study of Australian Children (LSAC).
Five thousand one hundred seven infants aged 3-19 months in 2004.
Maternal report of immunisation status: incompletely or fully immunised.
Overall, 9.3% (473) of infants were incompletely immunised; of these just 16% had mothers who disagreed with immunisation. Remaining analyses focussed on infants whose mother did not disagree with immunisation (N=4994) (of whom 8% [398] were incompletely immunised). Fifteen variables representing potential immunisation barriers and facilitators were available in LSAC; these were entered into a latent class model to identify distinct clusters (or 'classes') of barriers experienced by families. Five classes were identified: (1) 'minimal barriers', (2) 'lone parent, mobile families with good support', (3) 'low social contact and service information; psychological distress', (4) 'larger families, not using formal childcare', (5) 'child health issues/concerns'. Compared to infants from families experiencing minimal barriers, all other barrier classes had a higher risk of incomplete immunisation. For example, the adjusted risk ratio (RR) for incomplete immunisation was 1.51 (95% confidence interval: 1.08-2.10) among those characterised by 'low social contact and service information; psychological distress', and 2.47 (1.87-3.25) among 'larger families, not using formal childcare'.
Using the most recent data available for examining these issues in Australia, we found that the majority of incompletely immunised infants (in 2004) did not have a mother who disagreed with immunisation. Barriers to immunisation are heterogeneous, suggesting a need for tailored interventions.
研究澳大利亚父母在儿童免疫接种方面遇到的障碍。
对二手数据进行横断面分析。
具有全国代表性的澳大利亚儿童纵向研究(LSAC)。
2004年5107名年龄在3至19个月的婴儿。
母亲报告的免疫接种状况:未完全接种或已完全接种。
总体而言,9.3%(473名)婴儿未完全接种;其中只有16%的母亲不同意接种。其余分析聚焦于母亲不反对接种的婴儿(N = 4994)(其中8%[398名]未完全接种)。LSAC中有15个代表潜在免疫接种障碍和促进因素的变量;将这些变量纳入潜在类别模型,以识别家庭经历的不同障碍集群(或“类别”)。确定了五个类别:(1)“障碍最小”,(2)“单亲、流动且获得良好支持的家庭”,(3)“社交接触少、服务信息不足;心理困扰”,(4)“大家庭,未使用正规托儿服务”,(5)“儿童健康问题/担忧”。与经历障碍最小的家庭的婴儿相比,所有其他障碍类别未完全接种的风险更高。例如,以“社交接触少、服务信息不足;心理困扰”为特征的婴儿,未完全接种的调整风险比(RR)为1.51(95%置信区间:1.08 - 2.10),而“大家庭,未使用正规托儿服务”的婴儿这一比例为2.47(1.87 - 3.25)。
利用澳大利亚可用于研究这些问题的最新数据,我们发现(2004年)大多数未完全接种的婴儿的母亲并不反对接种。免疫接种障碍具有异质性,这表明需要采取针对性的干预措施。