Wysham Nicholas G, Miriovsky Benjamin J, Currow David C, Herndon James E, Samsa Gregory P, Wilcock Andrew, Abernethy Amy P
Division of Pulmonary, Allergy and Critical Care Medicine, Duke Cancer Institute, Duke University Medical Center, Durham, North Carolina, USA; Center for Learning Health Care, Duke Clinical Research Institute, Duke Cancer Institute, Duke University Medical Center, Durham, North Carolina, USA.
Division of Medical Oncology, Department of Medicine, Duke Cancer Institute, Duke University Medical Center, Durham, North Carolina, USA; Duke Cancer Care Research Program, Duke Cancer Institute, Duke University Medical Center, Durham, North Carolina, USA.
J Pain Symptom Manage. 2015 Oct;50(4):480-7. doi: 10.1016/j.jpainsymman.2015.04.015. Epub 2015 May 22.
Measurement of dyspnea is important for clinical care and research.
To characterize the relationship between the 0-10 Numerical Rating Scale (NRS) and four-level categorical Verbal Descriptor Scale (VDS) for dyspnea assessment.
This was a substudy of a double-blind randomized controlled trial comparing palliative oxygen to room air for relief of refractory breathlessness in patients with life-limiting illness. Dyspnea was assessed with both a 0-10 NRS and a four-level categorical VDS over the one-week trial. NRS and VDS responses were analyzed in cross section and longitudinally. Relationships between NRS and VDS responses were portrayed using descriptive statistics and visual representations.
Two hundred twenty-six participants contributed responses. At baseline, mild and moderate levels of breathlessness were reported by 41.9% and 44.6% of participants, respectively. NRS scores demonstrated increasing mean and median levels for increasing VDS intensity, from a mean (SD) of 0.6 (±1.04) for VDS none category to 8.2 (1.4) for VDS severe category. The Spearman correlation coefficient was strong at 0.78 (P < 0.0001). Based on the distribution of NRS scores within VDS categories, we calculated test characteristics of two different cutpoint models. Both models yielded 75% correct translations from NRS to VDS; however, Model A was more sensitive for moderate or greater dyspnea, with fewer misses downcoded.
There is strong correlation between VDS and NRS measures for dyspnea. Proposed practical cutpoints for the relationship between the dyspnea VDS and NRS are 0 for none, 1-4 for mild, 5-8 for moderate, and 9-10 for severe.
呼吸困难的测量对临床护理和研究很重要。
描述用于呼吸困难评估的0至10数字评定量表(NRS)与四级分类言语描述量表(VDS)之间的关系。
这是一项双盲随机对照试验的子研究,该试验比较了姑息性吸氧与室内空气对缓解晚期疾病患者难治性呼吸困难的效果。在为期一周的试验中,使用0至10 NRS和四级分类VDS对呼吸困难进行评估。对NRS和VDS的反应进行横断面分析和纵向分析。使用描述性统计和可视化表示法描绘NRS和VDS反应之间的关系。
226名参与者提供了反应。在基线时,分别有41.9%和44.6%的参与者报告有轻度和中度呼吸困难。NRS评分显示,随着VDS强度增加,平均和中位数水平升高,从VDS无类别时的平均(标准差)0.6(±1.04)到VDS严重类别时的8.2(1.4)。Spearman相关系数很强,为0.78(P<0.0001)。根据VDS类别内NRS评分的分布,我们计算了两种不同切点模型的检验特征。两种模型从NRS到VDS的正确转换率均为75%;然而,模型A对中度或更严重的呼吸困难更敏感,下调编码的漏诊较少。
VDS和NRS对呼吸困难的测量之间存在很强的相关性。建议的呼吸困难VDS和NRS之间关系的实际切点为:无=0,轻度=1至4,中度=5至8,重度=9至10。