Agani Zana Bajrami, Benedetti Alberto, Krasniqi Vjosa Hamiti, Ahmedi Jehona, Sejfija Zana, Loxha Mergime Prekazi, Murtezani Arben, Rexhepi Aida Namani, Ibraimi Zana
Department of Oral Surgery, Clinical Dentistry University Center of Kosova.
Department of Maxillofacial Surgery, University of Skopje-Macedonia.
Med Arch. 2015 Apr;69(2):117-22. doi: 10.5455/medarh.2015.117-122. Epub 2015 Apr 6.
The patients that are subjects to oral-surgical interventions produce large amounts of steroids in comparison with healthy patients which are not a subject to any dental intervention. The aim of research was to determine the level of stress hormone cortisol in serum, arterial blood pressure and arterial pulse, and to compare the effectiveness of the usage of lidocaine with adrenalin in comparison with lidocaine without adrenalin during the tooth extraction.
This clinical research includes patients with indication of tooth extraction divided in hypertensive and normotensive patients.
There is no important statistical distinction between groups, for the cortisol levels before, during and after tooth extraction regardless of the type of anesthetic used, while we registered higher values of systolic and diastolic values at hypertensive patients, regardless of the type of anesthetic.
There is significant systolic and diastolic blood pressure rise in both groups of patients hypertensive and normotensive patients, (regardless of anesthetic used with or without vasoconstrictor), who underwent tooth extraction. The special emphasize is attributed to hypertensive patients where these changes are more significant. As per cortisol level and pulse rate, our results indicate no significant statistical difference in between groups.
与未接受任何牙科干预的健康患者相比，接受口腔外科手术干预的患者会产生大量类固醇。本研究的目的是测定血清中应激激素皮质醇的水平、动脉血压和动脉脉搏，并比较拔牙过程中使用含肾上腺素利多卡因与不含肾上腺素利多卡因的效果。
本临床研究纳入有拔牙指征的患者，分为高血压患者和血压正常患者。
无论使用何种麻醉剂，拔牙前、拔牙期间和拔牙后两组患者的皮质醇水平均无显著统计学差异，而无论使用何种麻醉剂，高血压患者的收缩压和舒张压值均较高。
接受拔牙的高血压和血压正常两组患者（无论使用含或不含血管收缩剂的麻醉剂）的收缩压和舒张压均显著升高。特别强调的是高血压患者，这些变化更为显著。就皮质醇水平和脉搏率而言，我们的结果表明两组之间无显著统计学差异。
