Division of Dental Care, Instituto do Coração, Faculdade de Medicina da Universidade de São Paulo - São Paulo/SP, Brazil.
Clinics (Sao Paulo). 2009;64(3):177-82. doi: 10.1590/s1807-59322009000300005.
This study analyzes hemodynamic changes in patients with cardiac valvular diseases submitted to dental treatment under local anesthesia containing epinephrine.
This randomized clinical trial was performed at the Dental Division of the Instituto do Coração do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (Brazil). Patients were separated into two groups with the help of an aleatory number table: 2% plain lidocaine (PL, n= 31) and 2% lidocaine with epinephrine (1:100,000) (LE, n= 28). Blood pressure, heart rate, oxygenation and electrocardiogram data were all recorded throughout the procedure. State and trait anxiety levels were measured.
Fifty-nine patients were selected for the LE group (n=28), with an average age of 40.3 +/- 10.9, or for the PL group (n=31), age 42.2 +/- 10.3. No differences were shown in blood pressure, heart rate and pulse oximetry values before, during and after local anesthesia injection between the two groups. State and trait anxiety levels were not different. Arrhythmias observed before dental anesthesia did not change in shape or magnitude after treatment. Complaints of pain during the dental procedure were more frequent within the PL group, which received a higher amount of local anesthesia.
Lidocaine with epinephrine (1:100,000) provided effective local anesthesia. This treatment did not cause an increase in heart rate or blood pressure and did not cause any arrhythmic changes in patients with cardiac valvular diseases.
本研究分析了心脏瓣膜病患者在局部麻醉下接受含肾上腺素的牙科治疗时的血液动力学变化。
本随机临床试验在巴西圣保罗大学附属医院心脏病学研究所牙科分部进行。患者借助随机数字表分为两组:2% 盐酸利多卡因(PL,n=31)和 2% 盐酸利多卡因加肾上腺素(1:100000)(LE,n=28)。整个过程中记录血压、心率、氧合和心电图数据。测量状态和特质焦虑水平。
选择 LE 组(n=28)的 59 名患者平均年龄为 40.3 +/- 10.9 岁,或 PL 组(n=31)年龄为 42.2 +/- 10.3 岁。两组之间,局部麻醉注射前后血压、心率和脉搏血氧饱和度值没有差异。状态和特质焦虑水平没有差异。牙科麻醉前观察到的心律失常在治疗后形状或幅度没有变化。在 PL 组中,更多患者在接受更高剂量的局部麻醉时报告在牙科手术过程中感到疼痛。
肾上腺素(1:100000)利多卡因提供了有效的局部麻醉。这种治疗不会引起心率或血压升高,也不会引起心脏瓣膜病患者出现任何心律失常变化。