Adhami-Moghadam Farhad, Iran-Pour Elham
1. Dept. of Ophthalmology, Tehran Medical Branch, Islamic Azad University , Tehran, Iran.
2. Tehran Medical Branch, Islamic Azad University , Tehran, Iran.
Iran J Public Health. 2014 Apr;43(4):523-8.
To identify mental disorders and their prevalence in patients with retinitis pigmentosa (RP).
This descriptive study was carried out between January 2009 and January 2010 on 417 patients with RP, who were members of Iran RP Center. The necessary data were collected using questionnaires consisting two parts: The background characteristics and questions assessing the mental health and screening personality and psychosocial disorders, which were designed based on the Minnesota Multiphasic Personality Inventory. Data were analyzed using SPSS software with Chi-square test to assess the relationship between background characteristics and each mental disorder. Scores in the range of 30 and 70 were considered normal.
Patients with RP suffered from eight mental disorders with the following prevalence: Obsessive compulsive disorder (39.3%), schizophrenia (38.1%), antisocial personality (37.6%), paranoia (36.7%), hypochondrias (35.3%), depression (31.2%), hysteria (26.9%), and hypomania (23.7%). No one had all the eight mental disorders simultaneously. Statistical analysis showed no significant relationship between obsessive compulsive disorder, paranoia, depression, and hysteria and background characteristics. A significant association was found between schizophrenia and onset of RP (P = 0.047). Furthermore, a significant association was seen between hypochondrias and educational level (P = 0.026) as well as income (P = 0.037), and smoking (P = 0.009). There was also a significant association between hypomania and marital status (P = 0.027).
The findings showed that RP might lead to various mental disorders, especially obsessive compulsive disorder.
确定视网膜色素变性(RP)患者的精神障碍及其患病率。
这项描述性研究于2009年1月至2010年1月对417名RP患者进行,这些患者均为伊朗RP中心的成员。使用包含两部分的问卷收集必要数据:背景特征以及评估心理健康、筛查人格和心理社会障碍的问题,这些问题是基于明尼苏达多相人格量表设计的。使用SPSS软件进行数据分析,并采用卡方检验评估背景特征与每种精神障碍之间的关系。得分在30至70分之间被视为正常。
RP患者患有八种精神障碍,患病率如下:强迫症(39.3%)、精神分裂症(38.1%)、反社会人格(37.6%)、偏执狂(36.7%)、疑病症(35.3%)、抑郁症(31.2%)、癔症(26.9%)和轻躁狂(23.7%)。没有人同时患有所有八种精神障碍。统计分析表明,强迫症、偏执狂、抑郁症和癔症与背景特征之间无显著关系。发现精神分裂症与RP发病之间存在显著关联(P = 0.047)。此外,疑病症与教育水平(P = 0.026)、收入(P = 0.037)以及吸烟(P = 0.009)之间存在显著关联。轻躁狂与婚姻状况之间也存在显著关联(P = 0.027)。
研究结果表明,RP可能导致各种精神障碍,尤其是强迫症。