伴 Usher 综合征患儿：精神和行为障碍。
Children with Usher syndrome: mental and behavioral disorders.
机构信息
Department of Psychology, University of Copenhagen, Øster Farimagsgade 2A, København K, Denmark.
出版信息
Behav Brain Funct. 2012 Mar 27;8:16. doi: 10.1186/1744-9081-8-16.
BACKGROUND
Mental and behavioral disorders among adults with Usher syndrome have been discussed and reported in some case studies but no research has been reported on children with Usher syndrome.
METHODS
This article investigates the prevalence and characteristics of mental and behavioral disorders among 26 children, 3-17 years of age, with Usher syndrome.
RESULTS
Six of the 26 children were diagnosed with a mental or behavioral disorder (1 with schizophrenia and mild mental retardation, 1 with atypical autism and severe mental retardation, 1 with atypical autism and mild mental retardation, 1 with mild mental retardation, and 2 with conduct disorder). Another 3 children had had a mental or behavioral disorder previously in their childhood.
CONCLUSION
Even though vision impairment first manifests in late childhood, some children with Usher syndrome seem to develop mental and behavioral disorders during childhood. The aetiology and treatment of mental and behavioral disorders among children with Usher syndrome are discussed. Children with Usher syndrome and their parents may need clinical support during early childhood to prevent development of mental and behavioral disorders.
背景
一些病例研究已经讨论和报告了成年乌谢尔综合征患者的精神和行为障碍，但尚未有研究报告乌谢尔综合征儿童的此类障碍。
方法
本文调查了 26 名 3-17 岁乌谢尔综合征儿童的精神和行为障碍的患病率和特征。
结果
26 名儿童中有 6 名被诊断为精神或行为障碍（1 名患有精神分裂症和轻度智力障碍，1 名患有非典型自闭症和重度智力障碍，1 名患有非典型自闭症和轻度智力障碍，1 名患有轻度智力障碍，2 名患有品行障碍）。另有 3 名儿童在儿童时期曾患有精神或行为障碍。
结论
尽管视力障碍首先在儿童晚期出现，但一些乌谢尔综合征儿童似乎在儿童期就出现了精神和行为障碍。本文讨论了乌谢尔综合征儿童精神和行为障碍的病因和治疗方法。乌谢尔综合征儿童及其父母可能需要在幼儿期获得临床支持，以预防精神和行为障碍的发展。
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