经直肠前列腺穿刺活检后可吸收止血明胶海绵对止血的影响。
Effect on hemostasis of an absorbable hemostatic gelatin sponge after transrectal prostate needle biopsy.
作者信息
Kobatake Kohei, Mita Koji, Kato Masao
机构信息
Department of Urology, Hiroshima City Asa Hospital, Japan.
出版信息
Int Braz J Urol. 2015 Mar-Apr;41(2):337-43. doi: 10.1590/S1677-5538.IBJU.2015.02.22.
OBJECTIVES
To examine the usefulness of an absorbable hemostatic gelatin sponge for hemostasis after transrectal prostate needle biopsy.
SUBJECTS AND METHODS
The subjects comprised 278 participants who underwent transrectal prostate needle biopsy. They were randomly allocated to the gelatin sponge insertion group (group A: 148 participants) and to the non-insertion group (group B: 130 participants). In group A, the gelatin sponge was inserted into the rectum immediately after biopsy. A biopsy-induced hemorrhage was defined as a case in which a subject complained of bleeding from the rectum, and excretion of blood clots was confirmed. A blood test was performed before and after biopsy, and a questionnaire survey was given after the biopsy.
RESULTS
Significantly fewer participants in group A required hemostasis after biopsy compared to group B (3 (2.0%) vs. 11 (8.5%), P=0.029). The results of the blood tests and the responses from the questionnaire did not differ significantly between the two groups. In multivariate analysis, only "insertion of a gelatin sponge into the rectum" emerged as a significant predictor of hemostasis.
CONCLUSION
Insertion of a gelatin sponge into the rectum after transrectal prostate needle biopsy significantly increases hemostasis without increasing patient symptoms, such as pain and a sense of discomfort.
目的
探讨可吸收止血明胶海绵在经直肠前列腺穿刺活检术后止血中的应用价值。
对象与方法
研究对象为278例行经直肠前列腺穿刺活检的患者。将他们随机分为明胶海绵置入组（A组：148例）和非置入组（B组：130例）。A组在活检后立即将明胶海绵置入直肠。活检引起的出血定义为患者主诉直肠出血且确认有血凝块排出的情况。在活检前后进行血液检查，并在活检后进行问卷调查。
结果
与B组相比，A组活检后需要止血的患者明显更少（3例（2.0%）对11例（8.5%），P = 0.029）。两组的血液检查结果和问卷调查的回答没有显著差异。在多因素分析中，只有“将明胶海绵置入直肠”是止血的显著预测因素。
结论
经直肠前列腺穿刺活检后将明胶海绵置入直肠可显著提高止血效果，且不会增加患者的疼痛和不适感等症状。
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