Palminteri Enzo, Berdondini Elisa, Florio Mirko, Cucchiarale Giuseppina, Milan Gianluca, Valentino Francesco, Sedigh Omid, Di Pierro Giovanni B
Center for Urethral and Genitalia Reconstructive Surgery, Arezzo, Italy.
Department of Urology, Tor Vergata University, Rome, Italy.
Int J Urol. 2015 Sep;22(9):861-6. doi: 10.1111/iju.12822. Epub 2015 May 25.
To report our initial experience with urethra-sparing reconstruction combining dorsal preputial skin and ventral buccal mucosa grafts for tight bulbar urethral strictures.
Between November 2006 and September 2012, 26 patients with tight bulbar strictures underwent urethroplasty. Using a ventral urethrotomy approach, the two-sided urethral reconstruction was carried out avoiding the transection of urethra and augmenting the preserved urethral plate by dorsal preputial skin plus ventral buccal mucosa grafts. The primary outcome was the objective urinary result, defined as the absence of stricture recurrence. The outcome was considered a failure when any postoperative instrumentation was required. Postoperative sexual dysfunctions were investigated using a validated questionnaire.
Mean follow up was 30.1 months (range 12-79 months). Mean stricture length was 3.3 cm (range 1.5-6 cm). Mean length for dorsal preputial skin and ventral buccal mucosa grafts was 3.2 cm (range 2-7 cm) and 4.9 cm (range 4-6 cm), respectively. Of 26 cases, 23 (88.5%) were successful and three (11.5%) were failures with stricture recurrence. Failures were treated with perineal urethrostomy in one case, ventral buccal graft urethroplasty in one case and internal urethrotomy in one case. Among 12 sexually active men preoperatively, none reported postoperative penile curvature/shortening, impaired erection or dissatisfaction regarding erection; sexual activity was unaltered pre- and post-surgery.
In tight bulbar urethra strictures, the two-sided urethroplasty combining dorsal preputial skin and ventral buccal mucosa grafts provides a safe and effective semi-circumferential reconstruction by augmenting the preserved urethral plate, with no impact on sexual function.
报告我们采用阴茎背侧包皮皮肤和口腔颊黏膜腹侧移植联合保尿道重建治疗球部尿道狭窄的初步经验。
2006年11月至2012年9月,26例球部尿道狭窄患者接受了尿道成形术。采用腹侧尿道切开入路,行双侧尿道重建,避免横断尿道,并采用阴茎背侧包皮皮肤加口腔颊黏膜腹侧移植来扩大保留的尿道板。主要结果是客观的排尿结果,定义为无狭窄复发。若术后需要任何器械操作,则该结果视为失败。采用经过验证的问卷对术后性功能障碍进行调查。
平均随访30.1个月(范围12 - 79个月)。平均狭窄长度为3.3厘米(范围1.5 - 6厘米)。阴茎背侧包皮皮肤和口腔颊黏膜腹侧移植的平均长度分别为3.2厘米(范围2 - 7厘米)和4.9厘米(范围4 - 6厘米)。26例患者中,23例(88.5%)成功,3例(11.5%)失败并出现狭窄复发。1例失败患者接受了会阴尿道造口术,1例接受了口腔颊黏膜腹侧移植尿道成形术,1例接受了尿道内切开术。术前12例有性活动的男性中,无人报告术后阴茎弯曲/缩短、勃起功能受损或对勃起不满意;手术前后性功能未改变。
对于球部尿道狭窄,阴茎背侧包皮皮肤和口腔颊黏膜腹侧移植联合双侧尿道成形术通过扩大保留的尿道板提供了一种安全有效的半环形重建方法,且对性功能无影响。