Tanioka H, Terahara A, Furuta A, Machida T, Iio M, Sirakawa T, Zusho H
Rinsho Hoshasen. 1989 Oct;34(11):1365-70.
Symptoms in Ménière's disease are explained by hydrops of endolymphatic system with recurrent ruptures of the membranous labyrinth. The primary cause of the increased endolymphatic volume appears to be an imbalance between secretion and resorption of endolymph which may be due to an obstruction of the endolymphatic duct and sac, located in the vestibular aqueduct. Non-visualization or narrowing of the vestibular aqueduct of the paper have been demonstrated by conventional tomography and high resolution computed tomography (HR-CT). But the endolymphatic duct and sac can not be obtained by HR-CT and conventional tomography. Whereas, on MRI, these are identified. By MRI, we prospectively tried to demonstrate morphological alterations in 10 patients with Ménière's disease and in 4 patients with vestibular neuronitis. These were compared with a group of 20 normal men. Visualization of the endolymphatic duct and sac (vestibular aqueduct) on MRI was assessed. There was a distinctly decreased visualization of the vestibular aqueduct in the Ménière group and vestibular neuronitis group. We were able to confirm a statistically proven usefulness of the MRI technique in identifying an anatomical abnormality which is directly in correlation with the side of the lesion in cases of unilateral Ménière's disease.
梅尼埃病的症状是由内淋巴系统积水以及膜迷路反复破裂引起的。内淋巴液体积增加的主要原因似乎是内淋巴分泌与吸收之间的失衡，这可能是由于位于前庭导水管内的内淋巴管和内淋巴囊受阻所致。传统体层摄影术和高分辨率计算机断层扫描（HR-CT）已证实该文中前庭导水管不显影或变窄。但HR-CT和传统体层摄影术无法显示内淋巴管和内淋巴囊。而在MRI上可以识别这些结构。我们通过MRI前瞻性地试图证明10例梅尼埃病患者和4例前庭神经炎患者的形态学改变。将这些患者与20名正常男性组成的对照组进行比较。评估MRI上内淋巴管和内淋巴囊（前庭导水管）的显影情况。梅尼埃病组和前庭神经炎组的前庭导水管显影明显减少。我们能够证实MRI技术在识别解剖学异常方面具有统计学意义上的实用性，这种异常与单侧梅尼埃病患者的病变侧直接相关。
