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中国儿童白内障住院患者的十年病因学回顾

Ten-year etiologic review of Chinese children hospitalized for pediatric cataracts.

作者信息

Song Zixun, Zhao Daixin, Lv Cancan, Pu Wei, Xiao Wei

出版信息

Eye Sci. 2014 Sep;29(3):138-42.

PMID:26011968
Abstract

PURPOSE

Our aim was to obtain a better understanding of the etiologies and characteristics of pediatric cataracts treated at a single facility in China.

METHODS

Medical records accrued over a 10-year period (from August, 2003 to July, 2013) at Shengjing Hospital of China Medical University were reviewed retrospectively, identifying all patients treated for various subtypes of pediatric cataract. A database with 367 subjects under 14 years of age (598, including second-round surgeries) was generated.

RESULTS

Of this cohort (n = 367; males: 232, 63.2%; females: 135, 36.8%), 200 patients (54.5%) had bilateral cataracts, and 258 (70.3%) were under 3 years of age. In all age groups and in all subtypes of pediatric cataract, males were most commonly affected. Congenital cataract was the most prevalent subtype, accounting for 296 patients (80.7%). Most congenital cataracts were associated with other ocular or systemic abnormalities; and in 48 patients (16.22%), they were hereditary. Traumatic cataract was the most common subtype (85.92%) of acquired cataract. The few instances of cataracts due to steroids (n = 3) or to metabolic disorders (n = 2) occurred in males and involved both eyes.

CONCLUSION

The majority of pediatric cataracts in this patient population were congenital in nature. A significant lag in ophthalmologic evaluation of Chinese infants was evident and should be addressed by educating both children and parents on risk factors for cataract development. Regular assessments are especially important in children subjected to long-term systemic steroid treatments.

摘要

目的

我们的目的是更深入了解在中国一家机构接受治疗的小儿白内障的病因及特征。

方法

回顾性分析中国医科大学盛京医院10年期间(2003年8月至2013年7月)积累的病历,确定所有接受小儿白内障各亚型治疗的患者。建立了一个包含367名14岁以下受试者(598例,包括二次手术)的数据库。

结果

在该队列中(n = 367;男性:232例,63.2%;女性:135例,36.8%),200例患者(54.5%)患有双侧白内障,258例(70.3%)年龄在3岁以下。在所有年龄组和小儿白内障的所有亚型中,男性受影响最为常见。先天性白内障是最常见的亚型,占296例患者(80.7%)。大多数先天性白内障与其他眼部或全身异常有关;48例患者(16.22%)为遗传性。外伤性白内障是后天性白内障最常见的亚型(85.92%)。少数因类固醇(n = 3)或代谢紊乱(n = 2)导致的白内障病例发生在男性,且累及双眼。

结论

该患者群体中的大多数小儿白内障本质上是先天性的。中国婴儿眼科评估明显滞后,应通过对儿童及其家长进行白内障发生危险因素的教育来解决。对于接受长期全身类固醇治疗的儿童,定期评估尤为重要。

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