MERFISH 技术用于获取空间背景信息。
MERFISHing for spatial context.
机构信息
Institute for Medical Engineering & Science & Department of Chemistry, MIT, Cambridge, MA, USA; Ragon Institute of MGH, MIT, & Harvard, Cambridge, MA, USA; Broad Institute of MIT & Harvard, Cambridge, MA, USA.
New York Genome Center, New York, NY, USA; New York University, Center for Genomics and Systems Biology, New York, NY, USA.
出版信息
Trends Immunol. 2015 Jul;36(7):390-1. doi: 10.1016/j.it.2015.05.002. Epub 2015 May 23.
A new paper in Science by Zhuang and colleagues introduces multiplexed error-robust FISH (MERFISH). MERFISH extends single-molecule imaging techniques to profile the copy number and localization patterns of thousands of genes, representing a major advance for spatial transcriptomics, with exciting potential applications in immunology.
庄等人在《科学》杂志上发表的一篇新论文介绍了多重容错荧光原位杂交（MERFISH）。MERFISH 将单分子成像技术扩展到对数千个基因的拷贝数和定位模式进行分析，这是空间转录组学的重大进展，在免疫学中有令人兴奋的潜在应用。
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