Wang Jia, Xu Shu Zhen, Zha Yong, Bbu Ciugene F, Li Li Jun Yuan, Duan Yun You
Department of Ultrasound Diagnostics, Tangdu Hospital, Fourth Military Medical University, Xi'an, China (J.W., L.J.Y., Y.Y.D.); and Department of Special Examination, Tibet Corps Hospital, Chinese People's Armed Police Forces, Lhasa, China (S.Z.X., Y.Z., C.F.B.).
J Ultrasound Med. 2015 Jun;34(6):1107-14. doi: 10.7863/ultra.34.6.1107.
The purpose of this study was to sonographically assess the cerebral hemodynamic differences and changes after oxygen therapy in healthy youths of different ethnicities in Tibet.
Sixty-six healthy young Han visitors and 29 healthy young Tibetan residents were divided into 4 groups. Basic information was collected. Pulsed Doppler sonography was used to record the cerebral hemodynamic parameters for the internal carotid, vertebral, and middle cerebral arteries. The participants were then instructed to inhale oxygen, and basic information and cerebral hemodynamic parameters were recorded at 1, 2, 4, and 8 minutes, respectively. Differences in these parameters between groups were analyzed.
In comparisons of the flow parameters between sex-matched groups, the mean resistive index values for the internal carotid, vertebral, and middle cerebral arteries in the Han groups were significantly lower than those in the Tibetan groups (P <. 05). The mean peak systolic velocity, end-diastolic velocity, and mean velocity values for the middle cerebral artery in the Han groups were significantly higher than those in the Tibetan groups (P < .05). After oxygen uptake, there were no significant differences in the mean arterial oxygen saturation, heart rate, mean velocity, and resistive index values between the male groups, and similar changes were found for the arterial oxygen saturation and peak systolic velocity values between female groups after 8 minutes of oxygen uptake (P > .05).
Sonography is a useful modality for noninvasive and real-time detection of changes in cerebral hemodynamics and can provide reference values for the prevention and treatment of cerebrovascular diseases.
本研究旨在通过超声检查评估西藏不同民族健康青年吸氧治疗后脑血流动力学的差异及变化。
将66名健康汉族青年访客和29名健康藏族青年居民分为4组。收集基本信息。采用脉冲多普勒超声记录颈内动脉、椎动脉和大脑中动脉的脑血流动力学参数。然后指导参与者吸氧，并分别在1、2、4和8分钟时记录基本信息和脑血流动力学参数。分析各组间这些参数的差异。
在性别匹配组的血流参数比较中，汉族组颈内动脉、椎动脉和大脑中动脉的平均阻力指数值显著低于藏族组（P < 0.05）。汉族组大脑中动脉的平均收缩期峰值速度、舒张末期速度和平均速度值显著高于藏族组（P < 0.05）。吸氧后，男性组间平均动脉血氧饱和度、心率、平均速度和阻力指数值无显著差异，女性组吸氧8分钟后动脉血氧饱和度和收缩期峰值速度值也有类似变化（P > 0.05）。
超声检查是一种用于无创实时检测脑血流动力学变化的有用方法，可为脑血管疾病的防治提供参考值。
