Hardie E M, Carlson C S, Richardson D C
Department of Companion Animals and Special Species Medicine, College of Veterinary Medicine, North Carolina State University, Raleigh 27606.
Lasers Surg Med. 1989;9(6):595-601. doi: 10.1002/lsm.1900090610.
The effect of low dose neodymium:yttrium aluminum garnet (Nd:YAG) laser therapy on cartilage healing was studied. Partial- and full-thickness cartilage defects were surgically created in the femoral condyles of 20 adult dogs. The cartilage defects in one limb of each dog were exposed to 30 J of Nd:YAG laser energy. The dogs were euthanatized 1 week (n = 6), 1 month (n = 7), and 6 months (n = 7) after surgery. Plastic-embedded, undecalcified histologic sections of each cartilage defect were examined for evidence of cartilage healing. Special stains were used to determine the type of repair tissue present, and morphometric measurements of repair tissue were made. No effect of Nd:YAG laser therapy on cartilage healing was noted.
研究了低剂量钕钇铝石榴石(Nd:YAG)激光疗法对软骨愈合的影响。在20只成年犬的股骨髁上手术制造部分厚度和全厚度软骨缺损。每只犬一侧肢体的软骨缺损接受30焦耳的Nd:YAG激光能量照射。术后1周(n = 6)、1个月(n = 7)和6个月(n = 7)对犬实施安乐死。检查每个软骨缺损的塑料包埋、不脱钙组织学切片,以寻找软骨愈合的证据。使用特殊染色确定存在的修复组织类型,并对修复组织进行形态计量学测量。未观察到Nd:YAG激光疗法对软骨愈合有影响。