Volkov A A, Komarova E I, Kozlov A A, Bykov S A, Artiushkin A V
Med Radiol (Mosk). 1989 Dec;34(12):14-8.
The paper is devoted to the experience in diagnostic investigations using rose bengal, labeled with half-life 123I (123I-RB). The drug was synthesized in the B. P. Konstantinov Leningrad Institute of Nuclear Physics, USSR Academy of Sciences. Analysis of the results of investigations of 201 patients with diseases of the liver and biliary tracts revealed the advantages of 123I-RB over standard RPs of similar diagnostic purpose. Owing to low radiation exposure one could use higher activity (up to 120 MBq and more) of the drug. It made it possible to combine a study of the functional parameters of the hepatobiliary system and obtaining scintigraphic data on the structure of the liver and biliary tracts. 123I-RB is the best radiodiagnostic agent for a study of function and topography of the liver in patients with an increased blood level of bilirubin.
本文致力于使用半衰期为123I的放射性玫瑰红（123I-RB）进行诊断研究的经验。该药物由苏联科学院B.P.康斯坦丁诺夫列宁格勒核物理研究所合成。对201例肝脏和胆道疾病患者的研究结果分析表明，123I-RB比具有类似诊断目的的标准放射性药物具有优势。由于辐射暴露低，可以使用更高活度（高达120MBq及以上）的药物。这使得能够将肝胆系统功能参数的研究与获取肝脏和胆道结构的闪烁扫描数据相结合。123I-RB是研究胆红素水平升高患者肝脏功能和形态的最佳放射性诊断剂。
