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[用¹²³I标记的孟加拉玫瑰红的实验评估]

[Experimental evaluation of Bengal rose labeled with 123I].

作者信息

Volkov A A, Zaĭtsev V M, Kozlov A A, Alekseev E G, Gusel'nikov V S

出版信息

Med Radiol (Mosk). 1985 May;30(5):66-70.

PMID:3999956
Abstract

Experimental evaluation of Bengal rose labeled with short-lived 123I was performed. The best diagnostic feature in 123I-Bengal rose were shown during a scintigraphic study of the rabbit liver and biliferous tract conducted in simultaneous experiments with the use of the agent labeled with 131I and 99mTc-HIDA. These were a high quality of the image of the organs, a low radiation exposure and the absence of extrahepatic uptake of the agent, particularly under conditions of the ligament of the common bile duct. The absence of a noticeable toxic effect of 123I-Bengal rose was established in experiments on rats and mice.

摘要

对标记有短寿命123I的孟加拉玫瑰红进行了实验评估。在与标记有131I和99mTc-HIDA的试剂同时进行的实验中,对兔肝脏和胆道进行闪烁扫描研究时,显示出123I-孟加拉玫瑰红的最佳诊断特征。这些特征包括器官图像质量高、辐射暴露低以及试剂在肝外无摄取,尤其是在胆总管韧带的情况下。在大鼠和小鼠实验中证实了123I-孟加拉玫瑰红没有明显的毒性作用。

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