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[慢性肾功能不全患儿红细胞脂质过氧化及红细胞中维生素E水平]

[Peroxidation of erythrocyte lipids and levels of vitamin E in red blood cells in children with chronic renal insufficiency].

作者信息

Martino F, Lubrano R, Ruberto U, Mannarino O, Galletti E, D'Eufemia P, Giardini O

出版信息

Minerva Pediatr. 1989 Jun;41(6):315-7.

PMID:2601649
Abstract

The tocopherol and malonyldialdeyde levels in the erythrocytes of 15 children affected by chronic renal failure, free of therapy, have been studied. Decreased levels of the former and increased of the latter were found. These data indicate red blood cell lipids peroxidation, responsible, at least in part, of the reduced red blood cell survival and of chronic anemia.

摘要

对15名未接受治疗的慢性肾衰竭患儿红细胞中的生育酚和丙二醛水平进行了研究。发现前者水平降低,后者水平升高。这些数据表明红细胞脂质过氧化,这至少在一定程度上导致了红细胞存活期缩短和慢性贫血。

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