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孕期肥胖对母婴的相关风险:综述的系统评价

Risks associated with obesity in pregnancy, for the mother and baby: a systematic review of reviews.

作者信息

Marchi J, Berg M, Dencker A, Olander E K, Begley C

机构信息

School of Nursing and Midwifery, Trinity College Dublin, Dublin, Ireland.

Institute of Health and Care Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

出版信息

Obes Rev. 2015 Aug;16(8):621-38. doi: 10.1111/obr.12288. Epub 2015 May 28.

Abstract

Maternal obesity is linked with adverse outcomes for mothers and babies. To get an overview of risks related to obesity in pregnant women, a systematic review of reviews was conducted. For inclusion, reviews had to compare pregnant women of healthy weight with women with obesity, and measure a health outcome for mother and/or baby. Authors conducted full-text screening, quality assurance using the AMSTAR tool and data extraction steps in pairs. Narrative analysis of the 22 reviews included show gestational diabetes, pre-eclampsia, gestational hypertension, depression, instrumental and caesarean birth, and surgical site infection to be more likely to occur in pregnant women with obesity compared with women with a healthy weight. Maternal obesity is also linked to greater risk of preterm birth, large-for-gestational-age babies, foetal defects, congenital anomalies and perinatal death. Furthermore, breastfeeding initiation rates are lower and there is greater risk of early breastfeeding cessation in women with obesity compared with healthy weight women. These adverse outcomes may result in longer duration of hospital stay, with concomitant resource implications. It is crucial to reduce the burden of adverse maternal and foetal/child outcomes caused by maternal obesity. Women with obesity need support to lose weight before they conceive, and to minimize their weight gain in pregnancy.

摘要

孕妇肥胖与母婴不良结局相关。为了全面了解与肥胖孕妇相关的风险,我们对相关综述进行了系统回顾。纳入的综述必须将体重正常的孕妇与肥胖孕妇进行比较,并衡量母婴的健康结局。作者进行了全文筛选、使用AMSTAR工具进行质量保证以及双人数据提取步骤。对纳入的22篇综述进行的叙述性分析表明,与体重正常的孕妇相比,肥胖孕妇更易发生妊娠期糖尿病、先兆子痫、妊娠高血压、抑郁症、器械助产和剖宫产以及手术部位感染。孕妇肥胖还与早产、大于胎龄儿、胎儿缺陷、先天性异常和围产期死亡的风险增加有关。此外,与体重正常的女性相比,肥胖女性的母乳喂养启动率较低,且早期停止母乳喂养的风险更大。这些不良结局可能导致住院时间延长,同时带来资源方面的影响。减轻孕妇肥胖导致的母婴不良结局负担至关重要。肥胖女性在怀孕前需要获得支持以减轻体重,并在孕期尽量减少体重增加。

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