Zhang Meng, Yin Xianpeng, Tian Tian, Liang Yun, Li Weina, Lan Yue, Li Jian, Zhou Meimei, Ju Yong, Li Guangtao
Department of Chemistry, Tsinghua University, 100084 Beijing, China.
Chem Commun (Camb). 2015 Jun 25;51(50):10210-3. doi: 10.1039/c5cc02377g. Epub 2015 May 28.
A series of tetraphenylethylene (TPE)-bile acid conjugates was described. It was found that the synergetic combination of the distinct properties of TPE and bile acid units could directly afford uniform fluorescent vesicles with amphiphilic binding pockets in the membrane. This structural features of such vesicles provides a unique opportunity for facile construction of functional chemical systems through host-guest chemistry.
描述了一系列四苯乙烯(TPE)-胆汁酸共轭物。发现TPE和胆汁酸单元独特性质的协同组合能够直接提供在膜中具有两亲性结合口袋的均匀荧光囊泡。此类囊泡的这种结构特征为通过主客体化学轻松构建功能化学体系提供了独特的机会。