具有多种心血管危险因素的稳定个体早期冠状动脉病变的计算机断层扫描成像
Computed tomography imaging of early coronary artery lesions in stable individuals with multiple cardiovascular risk factors.
作者信息
Yang Xi, Huang Hong, Liu Hong, Zeng Zhi-Yu, Zhang Jie
机构信息
Division of Geriatrics Endocrinology, Guangxi Medical University, Nanning, China.
出版信息
Clinics (Sao Paulo). 2015 Apr;70(4):242-6. doi: 10.6061/clinics/2015(04)04.
OBJECTIVES
To investigate the prevalence, extent, severity, and features of coronary artery lesions in stable patients with multiple cardiovascular risk factors.
METHODS
Seventy-seven patients with more than 3 cardiovascular risk factors were suspected of having coronary artery disease. Patients with high-risk factors and 39 controls with no risk factors were enrolled in the study. The related risk factors included hypertension, impaired glucose tolerance, dyslipidemia, smoking history, and overweight. The characteristics of coronary lesions were identified and evaluated by 64-slice coronary computed tomography angiography.
RESULTS
The incidence of coronary atherosclerosis was higher in the high-risk group than in the no-risk group. The involved branches of the coronary artery, the diffusivity of the lesion, the degree of stenosis, and the nature of the plaques were significantly more severe in the high-risk group compared with the no-risk group (all p < 0.05).
CONCLUSION
Among stable individuals with high-risk factors, early coronary artery lesions are common and severe. Computed tomography has promising value for the early screening of coronary lesions.
目的
探讨具有多种心血管危险因素的稳定型患者冠状动脉病变的患病率、范围、严重程度及特征。
方法
77例具有3种以上心血管危险因素的患者被怀疑患有冠状动脉疾病。纳入有高危因素的患者以及39例无危险因素的对照者。相关危险因素包括高血压、糖耐量受损、血脂异常、吸烟史和超重。通过64层冠状动脉计算机断层扫描血管造影术识别并评估冠状动脉病变的特征。
结果
高危组冠状动脉粥样硬化的发生率高于无危险因素组。与无危险因素组相比，高危组冠状动脉受累分支、病变的弥漫性、狭窄程度及斑块性质均明显更严重（均p<0.05）。
结论
在具有高危因素的稳定个体中，早期冠状动脉病变常见且严重。计算机断层扫描对冠状动脉病变的早期筛查具有重要价值。
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