Radzikowski A, Józefowicz A, Kulus M, Zalewski T
Pediatr Pol. 1989 Mar;64(3):145-9.
Gluten challenge was performed in 22 coeliac children in the period of histological remission. Gluten in dose 0.5 g/kg was administered for 6 months. Before the Provocation Test over 60% of children have had body weight over 50 c for normal children in Warsaw. Standardized mean body weight (+ 0.13 +/- 1.1) and height (+ 0.04 +/- 1.05) of the investigated coeliac children did not differ significantly from the values of normal Warsaw population (p greater than 0.005). A 6 month provocation with gluten leading to the histological relapse did not affect body weight and height of tested children; over 50% have had body weight and height over 50 c. Mean standardized body weight (- 0.002 +/- 1.0) and height height (-0.07 +/- 0.91) did not differ significantly from the normal values (p greater than 0.05) and corresponding values before the provocation (p greater than 0.05). It seems that Provocation Test with gluten carried out in the above way does not inhibit physical development of children with coeliac disease.
对22名处于组织学缓解期的乳糜泻患儿进行了麸质激发试验。给予剂量为0.5 g/kg的麸质，持续6个月。在激发试验前，超过60%的患儿体重超过华沙正常儿童的第50百分位数。所研究的乳糜泻患儿的标准化平均体重（+0.13±1.1）和身高（+0.04±1.05）与华沙正常人群的值无显著差异（p>0.005）。为期6个月的麸质激发试验导致组织学复发，但未影响受试患儿的体重和身高；超过50%的患儿体重和身高超过第50百分位数。平均标准化体重（-0.002±1.0）和身高（-0.07±0.91）与正常值无显著差异（p>0.05），与激发试验前的相应值也无显著差异（p>0.05）。以上述方式进行的麸质激发试验似乎不会抑制乳糜泻患儿的身体发育。
