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一名儿童的朗格汉斯细胞组织细胞增多症——通过口腔表现确诊

Langerhans histiocytosis in a child - diagnosed by oral manifestations.

作者信息

Golai Shruti, Nimbeni Basavaraj, Patil Sandya Devi, Kakanur Madhu, Paul Santosh

机构信息

Assistant Professor, Department of Pedodontics & Preventive Dentistry, College of Dental Sciences, Chitwan Medical College and Teaching Hospital , Bharatpur, Chitwan, Nepal .

Professor and Head, Department of Pedodontics & Preventive Dentistry, KLE's Institute of Dental Sciences , Bengaluru, Karnataka, India .

出版信息

J Clin Diagn Res. 2015 Apr;9(4):ZD09-11. doi: 10.7860/JCDR/2015/12353.5786. Epub 2015 Apr 1.

Abstract

Langerhans Histiocytosis (LCH) is a rare reactive and proliferative disease of histiocytes with unknown etiology, characterized by excessive proliferation of histiocytes called Langerhans cells. It occurs mainly in children but occurrence in adults has also been reported. It manifests as punched out lesions in the skull, maxilla, mandible, sternum and other flat bones and causes rapid resorption of the alveolar bone leading to floating teeth appearance in the radiographs. This disease manifests initially in the oral cavity in most of the cases and can be diagnosed by careful clinical and radiological examination. Here, we present a case of LCH in a child which was diagnosed by a swelling in the mandibular region.

摘要

朗格汉斯细胞组织细胞增多症(LCH)是一种病因不明的罕见的组织细胞反应性增生性疾病,其特征是名为朗格汉斯细胞的组织细胞过度增殖。它主要发生于儿童,但也有成人发病的报道。其表现为颅骨、上颌骨、下颌骨、胸骨和其他扁骨的穿凿样病变,并导致牙槽骨迅速吸收,在X线片上呈现出牙漂浮的征象。在大多数病例中,这种疾病最初在口腔表现出来,通过仔细的临床和影像学检查可以确诊。在此,我们报告一例儿童朗格汉斯细胞组织细胞增多症,该病例通过下颌区域肿胀得以诊断。

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