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Cocaine receptors: in vivo labeling with 3H-(-)cocaine, 3H-WIN 35,065-2, and 3H-WIN 35,428.

作者信息

Scheffel U, Boja J W, Kuhar M J

机构信息

John Hopkins Medical Institutions, Baltimore, Maryland 21205.

出版信息

Synapse. 1989;4(4):390-2. doi: 10.1002/syn.890040415.

DOI:10.1002/syn.890040415
PMID:2603151
Abstract
摘要

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1
Cocaine receptors: in vivo labeling with 3H-(-)cocaine, 3H-WIN 35,065-2, and 3H-WIN 35,428.可卡因受体：用³H-(-)可卡因、³H-WIN 35,065-2和³H-WIN 35,428进行体内标记
Synapse. 1989;4(4):390-2. doi: 10.1002/syn.890040415.
2
Cocaine receptors labeled by [3H]2 beta-carbomethoxy-3 beta-(4-fluorophenyl)tropane.
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3
[3H]WIN 35,428 binding in the caudate nucleus of the rabbit: evidence for a single site on the dopamine transporter.[3H]WIN 35,428在兔尾状核中的结合：多巴胺转运体上单一位点的证据。
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Synthesis and receptor binding of cocaine analogs.可卡因类似物的合成与受体结合
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5
High affinity cocaine recognition sites on the dopamine transporter are elevated in fatal cocaine overdose victims.多巴胺转运体上的高亲和力可卡因识别位点在可卡因致命过量受害者中有所增加。
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6
Synthesis and ligand binding of cocaine isomers at the cocaine receptor.可卡因异构体在可卡因受体上的合成与配体结合
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7
3'-Chloro-3 alpha-(diphenylmethoxy)tropane but not 4'-chloro-3 alpha-(diphenylmethoxy)tropane produces a cocaine-like behavioral profile.3'-氯-3α-(二苯甲氧基)托烷而非4'-氯-3α-(二苯甲氧基)托烷产生类似可卡因的行为表现型。
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8
[3H]WIN 35,428 ([3H]CFT) binds to multiple charge-states of the solubilized dopamine transporter in primate striatum.[3H]WIN 35,428（[3H]CFT）与灵长类动物纹状体中溶解的多巴胺转运体的多种电荷状态结合。
J Pharmacol Exp Ther. 1995 Jun;273(3):1224-34.
9
Age-related reductions in [3H]WIN 35,428 binding to the dopamine transporter in nigrostriatal and mesolimbic brain regions of the fischer 344 rat.费希尔344大鼠黑质纹状体和中脑边缘脑区中，与多巴胺转运体结合的[3H]WIN 35,428随年龄增长而减少。
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Halogenated mazindol analogs as potential inhibitors of the cocaine binding site at the dopamine transporter.卤代马吲哚类似物作为多巴胺转运体上可卡因结合位点的潜在抑制剂。
J Med Chem. 1996 Dec 6;39(25):4935-41. doi: 10.1021/jm960288w.

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