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辐射相关损伤及其管理:最新进展

Radiation-related injuries and their management: an update.

作者信息

Wunderle Kevin, Gill Amanjit S

机构信息

Department of Radiology, Imaging Institute, Cleveland Clinic, Cleveland, Ohio.

Department of Interventional Radiology, Imaging Institute, Cleveland Clinic, Cleveland, Ohio.

出版信息

Semin Intervent Radiol. 2015 Jun;32(2):156-62. doi: 10.1055/s-0035-1549446.

Abstract

Ionizing radiation (in the form of X-rays) is used for the majority of procedures in interventional radiology. This review article aimed at promoting safer use of this tool through a better understanding of radiation dose and radiation effects, and by providing guidance for setting up a quality assurance program. To this end, the authors describe different radiation descriptive quantities and their individual strengths and challenges, as well as the biologic effects of ionizing radiation, including patient-related effects such as tissue reactions (previously known as deterministic effects) and stochastic effects. In this article, the clinical presentation, immediate management, and clinical follow-up of these injuries are also discussed. Tissue reactions are important primarily from the patients' perspective, whereas stochastic effects are most relevant for pediatric patients and from an occupational viewpoint. The factors affecting the likelihood of skin reaction (the most common tissue reaction) are described, and how this condition should be managed is discussed. Setting up a robust quality assurance program around radiation dose is imperative for effective monitoring and reduction of radiation exposure to patients and operators. Recommendations for the pre-, peri-, and postprocedure periods are given, including recommendations for follow-up of high-dose cases. Special conditions such as pregnancy and radiation recall are also discussed.

摘要

在介入放射学的大多数操作中,都会使用(X射线形式的)电离辐射。这篇综述文章旨在通过更好地理解辐射剂量和辐射效应,并提供建立质量保证计划的指导,来促进对该工具的更安全使用。为此,作者描述了不同的辐射描述量及其各自的优势和挑战,以及电离辐射的生物学效应,包括与患者相关的效应,如组织反应(以前称为确定性效应)和随机效应。本文还讨论了这些损伤的临床表现、即时处理和临床随访。组织反应主要从患者角度来看很重要,而随机效应对于儿科患者以及从职业角度来说最为相关。描述了影响皮肤反应(最常见的组织反应)可能性的因素,并讨论了应如何处理这种情况。围绕辐射剂量建立一个强大的质量保证计划对于有效监测和减少患者及操作人员的辐射暴露至关重要。给出了术前、术中和术后阶段的建议,包括对高剂量病例随访的建议。还讨论了诸如怀孕和辐射召回等特殊情况。

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