Galli Federica, Caputi Marcella, Gallucci Marcello, Termine Cristiano, Chiappedi Matteo, Balottin Umberto
Department of Health Sciences, University of Milan, Milan, Italy -
Headache Science Center and Department of Child Neurology and Psychiatry, "C. Mondino National Institute of Neurology" Foundation, IRCCS, Pavia, Italy -
Minerva Pediatr. 2017 Aug;69(4):231-238. doi: 10.23736/S0026-4946.16.04256-0. Epub 2015 Jun 4.
Headache and psychopathology (especially anxiety and mood disorders) are comorbid across the life span. The present study is a clinical contribution in the direction of studying the familial recurrence of headache, and the interplay of headache and psychopathology in children.
The clinical sample is composed by 130 headache patients (53 boys and 77 girls, age range 8-18), while the control group is composed by 87 healthy subjects from the general population (39 boys and 48 girls, age range 8-18). A structured interview according to International Classification for Headache Disorders-II criteria has been administered to the clinical group; the Child Behavior Checklist (CBCL) and the Self Administrated Psychiatric Scales for Children and Adolescents (SAFA) have been used in order to assess psychopathology in both groups.
The recurrence of headache in family members is confirmed by the present study, albeit limited to paternal side, χ2 (4, N.=130)=10.47, P=0.033. Results also showed that scores obtained by the clinical sample in CBCL and SAFA are generally higher than scores obtained by the control group, but without differences between headache sub-types. Finally, internalizing symptoms (anxiety and depression) in children correlate with mothers' point of view, r≥0.23, P<0.05, outlining a specific attunement between headache patients and their mothers.
Headache runs in families, with high level of psychological disorders. Mothers are particularly attuned with the psychological needs of their headache children.
头痛与精神病理学（尤其是焦虑和情绪障碍）在整个生命周期中都存在共病现象。本研究是在研究头痛的家族复发以及儿童头痛与精神病理学之间相互作用方面的一项临床贡献。
临床样本由130名头痛患者（53名男孩和77名女孩，年龄范围8 - 18岁）组成，而对照组由87名来自普通人群的健康受试者（39名男孩和48名女孩，年龄范围8 - 18岁）组成。已根据《国际头痛疾病分类第二版》标准对临床组进行了结构化访谈；使用儿童行为检查表（CBCL）和儿童青少年自评精神量表（SAFA）来评估两组的精神病理学情况。
本研究证实了家庭成员中头痛的复发，尽管仅限于父系一方，χ2（4，N = 130）= 10.47，P = 0.033。结果还表明，临床样本在CBCL和SAFA中获得的分数总体上高于对照组，但头痛亚型之间没有差异。最后，儿童的内化症状（焦虑和抑郁）与母亲的观点相关，r≥0.23，P < 0.05，这表明头痛患者与其母亲之间存在特定的协调性。
头痛在家族中具有遗传性，且伴有高水平的心理障碍。母亲们尤其能适应头痛孩子的心理需求。
