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破坏性行为障碍症状及其与一般人群儿童样本中对立违抗障碍和其他障碍的关联。

Disruptive Mood Dysregulation Disorder Symptoms and Association with Oppositional Defiant and Other Disorders in a General Population Child Sample.

作者信息

Mayes Susan D, Waxmonsky James D, Calhoun Susan L, Bixler Edward O

机构信息

Department of Psychiatry, Penn State College of Medicine , Hershey, Pennsylvania.

出版信息

J Child Adolesc Psychopharmacol. 2016 Mar;26(2):101-6. doi: 10.1089/cap.2015.0074. Epub 2016 Jan 8.

Abstract

OBJECTIVE

The new Diagnostic and Statistical Manual of Mental Disorders, 5th ed. (DSM-5) diagnosis, disruptive mood dysregulation disorder (DMDD), has generated appreciable controversy since its inception, primarily in regard to its validity as a distinct disorder from oppositional defiant disorder (ODD). The goal of our study was to determine if the two DSM-5 DMDD symptoms (persistently irritable or angry mood and severe recurrent temper outbursts) occurred independently of other disorders, particularly ODD. Other DSM-5 DMDD criteria were not assessed.

METHODS

Maternal ratings of the two DMDD symptoms, clinical diagnosis of ODD using DSM-5 symptom criteria, and psychological problem scores (anxiety, depression, oppositional behavior, conduct disorder, and attention-deficit/hyperactivity disorder [ADHD]) on the Pediatric Behavior Scale were analyzed in a population sample, 6-12 years of age (n = 665).

RESULTS

The prevalence of DMDD symptoms (irritable-angry mood and temper outbursts both rated by mothers as often or very often a problem) was 9%. In all, 92% of children with DMDD symptoms had ODD, and 66% of children with ODD had DMDD symptoms, indicating that it is very unlikely to have DMDD symptoms without ODD, but that ODD can occur without DMDD symptoms. Comorbid psychological problems (anxiety, depression, conduct disorder, and ADHD) in addition to ODD did not increase the risk of having DMDD symptoms beyond that for ODD alone. Only 3% of children with psychological problems other than ODD had DMDD symptoms.

CONCLUSIONS

Our general population findings are similar to those for a psychiatric sample, suggesting that DMDD cannot be differentiated from ODD based on symptomatology. Therefore, it is important to assess all DSM criteria and to examine for comorbid psychopathology when considering a diagnosis of DMDD. Our results support the recommendation made by the World Health Organization's International Classification of Diseases, 11th Revision (ICD-11) panel of experts that DMDD symptoms may be more appropriately classified as an ODD specifier than a separate diagnosis.

摘要

目的

新版《精神疾病诊断与统计手册》第5版(DSM-5)中的破坏性心境失调障碍(DMDD)自问世以来引发了相当大的争议,主要是关于其作为一种与对立违抗障碍(ODD)不同的独特疾病的有效性。我们研究的目的是确定DSM-5中DMDD的两个症状(持续易激惹或愤怒情绪以及严重反复的发脾气)是否独立于其他疾病出现,尤其是ODD。未评估其他DSM-5 DMDD标准。

方法

在一个6至12岁的人群样本(n = 665)中,分析了母亲对DMDD两个症状的评分、使用DSM-5症状标准对ODD的临床诊断以及儿童行为量表上的心理问题得分(焦虑、抑郁、对立行为、品行障碍和注意力缺陷多动障碍[ADHD])。

结果

DMDD症状(母亲将易激惹-愤怒情绪和发脾气均评定为经常或非常经常成为问题)的患病率为9%。总体而言,有DMDD症状的儿童中92%患有ODD,有ODD的儿童中66%有DMDD症状,这表明没有ODD而出现DMDD症状的可能性非常小,但ODD可以在没有DMDD症状的情况下出现。除ODD外的共病心理问题(焦虑、抑郁、品行障碍和ADHD)并未使出现DMDD症状的风险高于仅患有ODD的情况。仅有3%除ODD外有心理问题的儿童有DMDD症状。

结论

我们在普通人群中的研究结果与在精神病学样本中的结果相似,这表明无法基于症状学将DMDD与ODD区分开来。因此,在考虑DMDD诊断时,评估所有DSM标准并检查共病精神病理学很重要。我们的结果支持世界卫生组织《国际疾病分类》第11版(ICD-11)专家小组的建议,即DMDD症状可能更适合归类为ODD的一个特定类型,而非单独的诊断。

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