Lenoir P, De Meirleir L, Bougatef A, Marchand J, Sacré L
Department of Pediatrics, University of Brussels, Belgium.
Pediatr Neurol. 1989 Nov-Dec;5(6):370-2. doi: 10.1016/0887-8994(89)90051-9.
Candida albicans meningitis was found in an otherwise healthy 44-day-old premature infant whose birth weight was 1,860 gm. Almost no abnormal clinical or neurologic findings were present. The electroencephalogram, however, was abnormal. All previous body fluid cultures were negative. The combined use of amphotericin B and 5-fluorocytosine resulted in negative cerebrospinal fluid cultures after 3 weeks of therapy. Physical and psychomotor development remained normal on subsequent examination.
在一名出生体重为1860克、44天大的健康早产婴儿中发现了白色念珠菌性脑膜炎。几乎没有异常的临床或神经学表现。然而,脑电图是异常的。之前所有的体液培养均为阴性。两性霉素B和5-氟胞嘧啶联合使用3周后脑脊液培养结果转为阴性。后续检查显示体格和精神运动发育仍正常。