Patel Harsh, Madanieh Raef, Kosmas Constantine E, Vatti Satya K, Vittorio Timothy J
Department of Internal Medicine, SUNY Downstate School of Medicine, Brooklyn, NY, USA.
St. Francis Hospital - The Heart Center , Center for Advanced Cardiac Therapeutics, Roslyn, NY, USA.
Clin Med Insights Cardiol. 2015 May 21;9(Suppl 2):15-21. doi: 10.4137/CMC.S19708. eCollection 2015.
Left ventricular assist devices (LVADs), more importantly the continuous-flow subclass, have revolutionized the medical field by improving New York Heart Association (NYHA) functional class status, quality of life, and survival rates in patients with advanced systolic heart failure. From the first pulsatile device to modern day continuous-flow devices, LVADs have continued to improve, but they are still associated with several complications. These complications include infection, bleeding, thrombosis, hemolysis, aortic valvular dysfunction, right heart failure, and ventricular arrhythmias. In this article, we aim to review these complications to understand the most appropriate approach for their prevention and to discuss the available therapeutic modalities.
左心室辅助装置（LVADs），更重要的是连续血流型这类装置，通过改善晚期收缩性心力衰竭患者的纽约心脏协会（NYHA）心功能分级状态、生活质量和生存率，给医学领域带来了变革。从首个搏动型装置到现代的连续血流装置，LVADs一直在不断改进，但它们仍与多种并发症相关。这些并发症包括感染、出血、血栓形成、溶血、主动脉瓣功能障碍、右心衰竭和室性心律失常。在本文中，我们旨在回顾这些并发症，以了解预防它们的最合适方法，并讨论现有的治疗方式。
