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腹主动脉瘤腔内修复术后移植物移位的系统评价与Meta分析

Systematic review and meta-analysis of migration after endovascular abdominal aortic aneurysm repair.

作者信息

Spanos Konstantinos, Karathanos Christos, Saleptsis Vasileios, Giannoukas Athanasios D

机构信息

Department of Vascular Surgery, University Hospital of Larissa, Faculty of Medicine, School of Health Sciences, University of Thessaly, Larissa, Greece

Department of Vascular Surgery, University Hospital of Larissa, Faculty of Medicine, School of Health Sciences, University of Thessaly, Larissa, Greece.

出版信息

Vascular. 2016 Jun;24(3):323-36. doi: 10.1177/1708538115590065. Epub 2015 Jun 8.

DOI:10.1177/1708538115590065
PMID:26056151
Abstract

AIM

To identify patients who are under higher threat for migration because of an old generation stent graft application.

METHODS

A systematic review and meta-analysis of the literature was undertaken to identify all studies which included older generation endografts and data reporting on graft migration after EVAR. Outcome data were pooled and combined, and were calculated using fixed or random effects models.

RESULTS

From 2000 to 2014, 22 retrospective studies were identified reporting on stent- graft migration after EVAR (8.6%). From those patients, 39% received re-intervention with the mean time of identification ranging from 12 to 36 months. Six of these retrospective nonrandomized studies were eligible for meta-analysis. AAA diameter (AAA diameter: 0.719 mm; 95% confidence interval [CI]: 0.00065-1.4384 mm; p = 0.00497) and neck length (neck length: 4.36 mm; 95% CI: 1.3277-7.394; p = 0.0048) were the only significant factors associated with stent- graft migration. Neck diameter and neck angulation did not have any important influence on stent-graft migration.

CONCLUSIONS

Patients with large AAA and short necks who were treated with older generation stent grafts such as AneurX and Talent are in higher risk for endograft migration than others. Stent- graft migration consists of an insidious and underestimated threat.

摘要

目的

识别因使用老式支架型人工血管而面临更高移植物迁移风险的患者。

方法

对文献进行系统回顾和荟萃分析,以确定所有纳入老式腔内移植物以及关于腔内修复术后移植物迁移数据报告的研究。汇总并合并结果数据,使用固定效应模型或随机效应模型进行计算。

结果

2000年至2014年,共识别出22项关于腔内修复术后支架型人工血管迁移的回顾性研究(8.6%)。在这些患者中,39%接受了再次干预,识别的平均时间为12至36个月。其中6项回顾性非随机研究符合荟萃分析条件。腹主动脉瘤直径(腹主动脉瘤直径:0.719毫米;95%置信区间[CI]:0.00065 - 1.4384毫米;p = 0.00497)和颈部长度(颈部长度:4.36毫米;95% CI:1.3277 - 7.394;p = 0.0048)是与支架型人工血管迁移相关的仅有的显著因素。颈部直径和颈部角度对支架型人工血管迁移没有任何重要影响。

结论

使用AneurX和Talent等老式支架型人工血管治疗的大腹主动脉瘤和短颈部患者,与其他患者相比,发生腔内移植物迁移的风险更高。支架型人工血管迁移构成了一种隐匿且被低估的威胁。

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