Nagarajappa Ramesh, Pujara Piyush, Sharda Archana J, Asawa Kailash, Tak Mridula, Aapaliya Pankaj, Bhanushali Nikhil
Dept. of Public Health Dentistry, Pacific Dental College and Hospital, Airport Road, Debari, Udaipur - 313024, Rajasthan, India.
Iran J Public Health. 2013 Aug;42(8):813-8.
Long-term ingestion of large amounts of fluoride can lead to potentially severe skeletal problems and neurological consequences. The study was conducted to assess and compare intelligence quotient of children living in high and low fluoride areas in Kutch, Gujarat, India.
A cross-sectional descriptive survey was conducted among 100 school children aged 8 to 10 years, living in Kutch District, Gujarat, India during July 2012. Mundra (2.4 to 3.5 mg/L) and Bhuj (0.5mg/L) were the two villages randomly selected to represent the high and low water fluoride areas respectively. Seguin Form Board Test was used to assess the intelligence quotient (IQ) level of children. Descriptive statistics and independent sample t-test was used for analysis.
Mean scores for average, shortest and total timing category were found to be significantly higher (P<0.05) among children living in Mundra (30.45±4.97) than those living in Bhuj (23.20±6.21). Mean differences at 95% confidence interval for these timings were found to be 7.24, 7.28 and 21.78 respectively. In both the villages, females had lower mean timing scores than males but the difference was not statistically significant (P>0.05).
Chronic exposure to high levels of fluoride in water was observed to be associated with lower intelligence quotient.
长期大量摄入氟化物可能导致潜在的严重骨骼问题和神经方面的后果。本研究旨在评估和比较印度古吉拉特邦库奇地区高氟和低氟地区儿童的智商。
2012年7月,在印度古吉拉特邦库奇地区对100名8至10岁的在校儿童进行了一项横断面描述性调查。分别随机选取蒙德拉(氟含量为2.4至3.5毫克/升)和布杰(氟含量为0.5毫克/升)两个村庄,分别代表高氟和低氟水区。采用塞金形板测验评估儿童的智商水平。使用描述性统计和独立样本t检验进行分析。
发现蒙德拉地区儿童(30.45±4.97)在平均、最短和总计时类别方面的平均得分显著高于布杰地区儿童(23.20±6.21)(P<0.05)。这些计时在95%置信区间的平均差异分别为7.24、7.28和21.78。在两个村庄中,女性的平均计时得分均低于男性,但差异无统计学意义(P>0.05)。
观察到长期接触高氟水与较低的智商有关。