Ivičević Nada, Roje Željka, Kljajić Zlatko, Bojić Lovro, Kardum Goran, Omero Lada, Račić Goran
Acta Clin Croat. 2015 Mar;54(1):25-9.
The aim of this study was to assess the prevalence of oral allergy syndrome (OAS) in patients with seasonal allergic rhinitis (SAR) and the possible risk factors for its development. This cross-sectional study was conducted in primary care offices in the Split-Dalmatia County during the period from March 1 to September 30, 2012. Data sources were medical history with confirmation of SAR (positive skin-prick test to seasonal inhalant allergens: grass, tree and weed pollens), anthropometric patient data (age, sex, weight and height), and a questionnaire in which patients evaluated their nasal and ocular symptoms, comorbidities and lifestyle. The χ2-test, Pearson χ2-test, Spearman's rho correlation coefficient and Kolmogorov-Smirnov test were used on statistical analysis. The prevalence of OAS was 45.7%. The risk factors for OAS development were diabetes (p < 0.001), severity of nasal symptoms (p < 0.05) and severity of ocular symptoms (p < 0.001). In conclusion, the prevalence of OAS in the Split-Dalmatia County is very high. The risks factors for OAS in patients with SAR are diabetes and severity of nasal and ocular symptoms.
本研究旨在评估季节性变应性鼻炎（SAR）患者中口腔过敏综合征（OAS）的患病率及其发生的可能危险因素。这项横断面研究于2012年3月1日至9月30日期间在斯普利特 - 达尔马提亚县的初级保健办公室进行。数据来源包括确诊为SAR的病史（对季节性吸入性变应原：草、树和杂草花粉的皮肤点刺试验呈阳性）、患者人体测量数据（年龄、性别、体重和身高）以及一份问卷，患者在问卷中评估了他们的鼻和眼部症状、合并症及生活方式。统计分析采用χ2检验、Pearson χ2检验、Spearman秩相关系数和Kolmogorov - Smirnov检验。OAS的患病率为45.7%。OAS发生的危险因素为糖尿病（p < 0.001）、鼻部症状严重程度（p < 0.05）和眼部症状严重程度（p < 0.001）。总之，斯普利特 - 达尔马提亚县OAS的患病率非常高。SAR患者中OAS的危险因素是糖尿病以及鼻和眼部症状的严重程度。
