Bedolla-Barajas M, Kestler-Gramajo A, Alcalá-Padilla G, Morales-Romero J
Servicio de Alergia e Inmunología Clínica, Nuevo Hospital Civil de Guadalajara "Dr. Juan I. Menchaca", Salvador de Quevedo y Zubieta No. 750, Colonia La Perla, Guadalajara, Jalisco, C. P. 44340, Mexico.
Servicio de Alergología e Inmunología Clínica, Hospital Civil de Guadalajara "Fray Antonio Alcalde", Coronel Calderón No. 777, Colonia El Retiro, Guadalajara, Jalisco, C. P. 44280, Mexico.
Allergol Immunopathol (Madr). 2017 Mar-Apr;45(2):127-133. doi: 10.1016/j.aller.2016.04.017. Epub 2016 Aug 24.
The oral allergy syndrome (OAS) is a particular type of food allergy rarely explored in the paediatric population that is already considered an adult problem.
Identify the prevalence of OAS, symptoms and pollen species associated with its presence in children affected by allergic diseases.
A cross-sectional study was conducted. Consecutive sampling included children from 6 to 14 years who needed allergy treatment for the first time. A structured questionnaire was carried out to collect demographic and clinical data and history of OAS. Besides sensitisation to various allergens, the skin prick-by-prick test was performed to corroborate sensitisation to food related to OAS. Prevalence of OAS and its association with pollens was established following the covariate adjusted logistic regression.
267 subjects were included. Overall prevalence of OAS was 8.9% (95%CI 6.1-13.1%). Prevalence of OAS for allergic rhinitis and asthma were 8.8% and 9.1%, respectively. In patients sensitised to pollen, the prevalence ranged from 9.6% to 12.2% depending on the type of pollen. 62.5% of children with OAS were sensitive to pineapple. After adjusting for gender and family history of atopic disease, trees from the Quercus species showed an association with OAS (OR=2.7, 95%CI 1.2-6.2).
OAS is not uncommon in our environment. Pineapple, a typical fruit from the region, was the main food related. Quercus sp., but not birch nor olive, was the pollen associated with this syndrome.
口腔过敏综合征（OAS）是一种特殊类型的食物过敏，在儿科人群中很少被研究，而人们通常认为这是一个成人问题。
确定口腔过敏综合征的患病率、症状以及与患有过敏性疾病儿童的口腔过敏综合征相关的花粉种类。
开展了一项横断面研究。连续抽样纳入了6至14岁首次需要进行过敏治疗的儿童。进行了一份结构化问卷以收集人口统计学和临床数据以及口腔过敏综合征病史。除了对各种过敏原的致敏情况外，还进行了逐点皮肤点刺试验以证实对与口腔过敏综合征相关食物的致敏情况。在进行协变量调整的逻辑回归后确定口腔过敏综合征的患病率及其与花粉的关联。
纳入了267名受试者。口腔过敏综合征的总体患病率为8.9%（95%置信区间6.1 - 13.1%）。过敏性鼻炎和哮喘患者的口腔过敏综合征患病率分别为8.8%和9.1%。在对花粉致敏的患者中，根据花粉类型，患病率在9.6%至12.2%之间。62.5%的口腔过敏综合征儿童对菠萝敏感。在调整了性别和特应性疾病家族史后，栎属树木显示与口腔过敏综合征有关联（比值比=2.7，95%置信区间1.2 - 6.2）。
在我们的环境中，口腔过敏综合征并不罕见。该地区典型的水果菠萝是主要相关食物。与该综合征相关的花粉是栎属植物，而非桦树或橄榄树。
