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本文引用的文献

1
Can platelet indices predict obstruction level of pulmonary vascular bed in patients with acute pulmonary embolism?血小板指标能否预测急性肺栓塞患者肺血管床的阻塞程度?
Clin Respir J. 2014 Jan;8(1):33-40. doi: 10.1111/crj.12031. Epub 2013 Jul 31.
2
Predictive value of mean platelet volume in young patients with non-ST-segment elevation acute coronary syndromes: a retrospective observational study.平均血小板体积在非ST段抬高型急性冠状动脉综合征年轻患者中的预测价值:一项回顾性观察研究。
Anadolu Kardiyol Derg. 2013 Feb;13(1):57-61. doi: 10.5152/akd.2013.007. Epub 2012 Oct 19.
3
Mean platelet volume and D-dimer in patients with suspected deep venous thrombosis.疑似深静脉血栓形成患者的血小板平均体积和 D-二聚体。
J Thromb Thrombolysis. 2012 Aug;34(2):283-7. doi: 10.1007/s11239-012-0746-2.
4
Acute pulmonary embolism: the clinical conundrum.急性肺栓塞:临床难题。
Chin Med J (Engl). 2012 Jan;125(2):352-66.
5
Silent pulmonary embolism in patients with proximal deep vein thrombosis in the lower limbs.下肢近端深静脉血栓形成患者的无症状肺栓塞。
J Thromb Haemost. 2012 Apr;10(4):564-71. doi: 10.1111/j.1538-7836.2012.04648.x.
6
Diagnostic approach to pulmonary embolism in a rural emergency department.
Can J Rural Med. 2012 Winter;17(1):17-20.
7
Mean platelet volume is increased in patients with deep vein thrombosis.平均血小板体积在深静脉血栓形成患者中增加。
Clin Appl Thromb Hemost. 2012 Jul;18(4):427-30. doi: 10.1177/1076029611427437. Epub 2011 Nov 22.
8
Elevated mean platelet volume is associated with impaired coronary microvascular function in patients with idiopathic dilated cardiomyopathy.血小板平均体积升高与特发性扩张型心肌病患者的冠状动脉微血管功能障碍有关。
Platelets. 2012;23(3):177-83. doi: 10.3109/09537104.2011.611273. Epub 2011 Sep 13.
9
Platelet indices in patients with acute pulmonary embolism.急性肺栓塞患者的血小板指标。
Scand J Clin Lab Invest. 2011 Apr;71(2):163-7. doi: 10.3109/00365513.2010.547596. Epub 2011 Jan 5.
10
Increased mean platelet volume in Behçet's disease with thrombotic tendency.伴有血栓形成倾向的白塞病患者平均血小板体积增加。
Tohoku J Exp Med. 2010 Jun;221(2):119-23. doi: 10.1620/tjem.221.119.

急诊科急性肺栓塞的一种新诊断标志物:平均血小板体积。

A new diagnostic marker for acute pulmonary embolism in emergency department: mean platelet volume.

作者信息

Talay Fahrettin, Ocak Tarık, Alcelik Aytekin, Erkuran Kurşat, Akkaya Akcan, Duran Arif, Demirhan Abdullah, Kar Kurt Ozlem, Asuk Zehra

机构信息

Department of Chest Diseases, Abant Izzet Baysal Medical Faculty, Bolu, Turkey.

Department of Emergency Medicine, Abant Izzet Baysal Medical Faculty, Bolu, Turkey.

出版信息

Afr Health Sci. 2014 Mar;14(1):94-9. doi: 10.4314/ahs.v14i1.15.

DOI:10.4314/ahs.v14i1.15
PMID:26060464
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4449081/
Abstract

OBJECTIVE

To investigate the diagnostic importance of mean platelet volume (MPV) on acute pulmonary embolism (APE) in the emergency Department (ED).

METHODS

Subjects were selected from patients admitted to ED with clinically suspected APE. Demographic, anthropometric and serologic data were collected for each patient.

RESULTS

A total of 315 consecutive patients were analyzed, including 150 patients (53.44 ± 15.14 y; 92 men/58 women) in APE group and 165 patients (49.80 ±13.76y; 94 men/71 women) in the control group. MPV in the APE group was significantly higher than in the control group (9.42±1.22 fl vs. 8.04±0.89 fl, p<0.0001). The best cut-off values for MPV when predicting APE in patients with clinically suspected APE presenting at the ED were 8.55 fl (sensitivity 82.2%; specificity 52.3%).

CONCLUSIONS

MPV is a helpful parameter for the diagnosis of APE in ED, for the first time in the literature.

摘要

目的

探讨平均血小板体积(MPV)在急诊科对急性肺栓塞(APE)的诊断价值。

方法

选取急诊科临床怀疑为APE的患者。收集每位患者的人口统计学、人体测量学和血清学数据。

结果

共分析了315例连续患者,其中APE组150例(53.44±15.14岁;男92例/女58例),对照组165例(49.80±13.76岁;男94例/女71例)。APE组的MPV显著高于对照组(9.42±1.22 fl对8.04±0.89 fl,p<0.0001)。急诊科临床怀疑为APE的患者中,MPV预测APE的最佳截断值为8.55 fl(敏感性82.2%;特异性52.3%)。

结论

本文首次表明,MPV是急诊科诊断APE的一个有用参数。