急诊科急性肺栓塞的一种新诊断标志物：平均血小板体积。
A new diagnostic marker for acute pulmonary embolism in emergency department: mean platelet volume.
作者信息
Talay Fahrettin, Ocak Tarık, Alcelik Aytekin, Erkuran Kurşat, Akkaya Akcan, Duran Arif, Demirhan Abdullah, Kar Kurt Ozlem, Asuk Zehra
机构信息
Department of Chest Diseases, Abant Izzet Baysal Medical Faculty, Bolu, Turkey.
Department of Emergency Medicine, Abant Izzet Baysal Medical Faculty, Bolu, Turkey.
出版信息
Afr Health Sci. 2014 Mar;14(1):94-9. doi: 10.4314/ahs.v14i1.15.
OBJECTIVE
To investigate the diagnostic importance of mean platelet volume (MPV) on acute pulmonary embolism (APE) in the emergency Department (ED).
METHODS
Subjects were selected from patients admitted to ED with clinically suspected APE. Demographic, anthropometric and serologic data were collected for each patient.
RESULTS
A total of 315 consecutive patients were analyzed, including 150 patients (53.44 ± 15.14 y; 92 men/58 women) in APE group and 165 patients (49.80 ±13.76y; 94 men/71 women) in the control group. MPV in the APE group was significantly higher than in the control group (9.42±1.22 fl vs. 8.04±0.89 fl, p<0.0001). The best cut-off values for MPV when predicting APE in patients with clinically suspected APE presenting at the ED were 8.55 fl (sensitivity 82.2%; specificity 52.3%).
CONCLUSIONS
MPV is a helpful parameter for the diagnosis of APE in ED, for the first time in the literature.
目的
探讨平均血小板体积（MPV）在急诊科对急性肺栓塞（APE）的诊断价值。
方法
选取急诊科临床怀疑为APE的患者。收集每位患者的人口统计学、人体测量学和血清学数据。
结果
共分析了315例连续患者，其中APE组150例（53.44±15.14岁；男92例/女58例），对照组165例（49.80±13.76岁；男94例/女71例）。APE组的MPV显著高于对照组（9.42±1.22 fl对8.04±0.89 fl，p<0.0001）。急诊科临床怀疑为APE的患者中，MPV预测APE的最佳截断值为8.55 fl（敏感性82.2%；特异性52.3%）。
结论
本文首次表明，MPV是急诊科诊断APE的一个有用参数。
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