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高散射组织中光传播的蒙特卡罗建模——II:与体模测量结果的比较

Monte Carlo modeling of light propagation in highly scattering tissues--II: Comparison with measurements in phantoms.

作者信息

Flock S T, Wilson B C, Patterson M S

出版信息

IEEE Trans Biomed Eng. 1989 Dec;36(12):1169-73. doi: 10.1109/10.42107.

DOI:10.1109/10.42107
PMID:2606491
Abstract

Measurements of the fluence-depth distributions and of the diffuse reflectance of 633 nm light have been made in liquid media with optical properties similar to soft tissues. The results are compared with predictions of Monte Carlo computer calculations in order to test the adequacy of Monte Carlo modeling of light transport in tissue. Except at extremely high albedo, the experimental data and the Monte Carlo results agree well for the depth dependence of the fluence as a function of incident light beam diameter and optical absorption and scattering, and for the dependence of the diffuse reflectance on the albedo. The absolute experimental values for the fluence must be renormalized by a factor which varies with the albedo in order to match the model values, and the possible sources of this discrepancy are discussed.

摘要

已在光学特性与软组织相似的液体介质中测量了633nm光的注量-深度分布和漫反射率。将结果与蒙特卡罗计算机计算的预测值进行比较,以检验蒙特卡罗对组织中光传输建模的充分性。除了在极高反照率的情况下,对于注量随入射光束直径、光吸收和散射的深度依赖性,以及漫反射率随反照率的依赖性,实验数据和蒙特卡罗结果吻合得很好。注量的绝对实验值必须通过一个随反照率变化的因子进行重新归一化,才能与模型值匹配,并讨论了这种差异可能的来源。

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