Higueras Manuel, Puig Pedro, Ainsbury Elizabeth A, Vinnikov Volodymyr A, Rothkamm Kai
Public Health England Centre for Radiation, Chemical and Environmental Hazards, Chilton, Didcot, Oxon OX11 0RQ, UK Departament de Matemàtiques, Universitat Autònoma de Barcelona, Barcelona, Spain
Departament de Matemàtiques, Universitat Autònoma de Barcelona, Barcelona, Spain.
Radiat Prot Dosimetry. 2016 Mar;168(3):330-6. doi: 10.1093/rpd/ncv356. Epub 2015 Jun 11.
A new zero-inflated Poisson model is introduced for the estimation of partial body irradiation dose and fraction of body irradiated. The Bayes factors are introduced as tools to help determine whether a data set of chromosomal aberrations obtained from a blood sample reflects partial or whole body irradiation. Two examples of simulated cytogenetic radiation exposure data are presented to demonstrate the usefulness of this methodology in cytogenetic biological dosimetry.
引入了一种新的零膨胀泊松模型,用于估计局部身体照射剂量和身体受照射的比例。引入贝叶斯因子作为工具,以帮助确定从血液样本获得的染色体畸变数据集反映的是局部还是全身照射。给出了两个模拟细胞遗传学辐射暴露数据的例子,以证明该方法在细胞遗传学生物剂量测定中的实用性。