Nicklas B J, Hackney A C, Sharp R L
Exercise Biochemistry Laboratory, Iowa State University, Ames 50010.
Int J Sports Med. 1989 Aug;10(4):264-9. doi: 10.1055/s-2007-1024913.
Six eumenorrheic females (age = 26.3 +/- 2.4 yrs; X +/- SE) exercised until exhaustion (EE; 70% VO2max) at the midluteal (LP, 7-8 days after ovulation) and midfollicular (FP, days 7-8) phases of their menstrual cycles. Phases were confirmed by estradiol and progesterone concentrations. Each EE test was preceded by a depletion exercise bout (DE; 90 min, 60% VO2max and 4 x 1 min, 100% VO2max) and 3 days of rest/diet control. Muscle biopsies 1% (vastus lateralis) were taken post-DE, pre-EE, and post-EE and then analyzed for glycogen content. There was a strong tendency (P less than 0.07) for EE duration to be greater during LP (139.2 +/- 14.9 min) than FP (126 +/- 17.5 min). Glycogen repletion (pre-EE minus post-DE) following DE was greater (P = 0.05) during the LP than FP (88.2 +/- 4.7 vs 72.8 +/- 5.7 mumol/g w. w. muscle). However, EE glycogen utilization (pre-EE minus post-EE/EE time) did not differ between phases (LP = 0.41 +/- 0.08 mumol/g w. w. muscle/min vs FP = 0.33 +/- 0.11 mumol/g w. w. muscle/min; P = 0.17). The results suggest that exercise performance and muscle glycogen content are enhanced during the LP of the menstrual cycle. These findings imply athletic performance may be affected by the phases of the menstrual cycle.
六名月经周期正常的女性（年龄 = 26.3 ± 2.4岁；均值±标准误）在月经周期的黄体中期（LP，排卵后7 - 8天）和卵泡中期（FP，第7 - 8天）进行运动直至力竭（EE；70%最大摄氧量）。通过雌二醇和孕酮浓度确认所处阶段。每次力竭运动测试前先进行一次耗尽运动（DE；90分钟，60%最大摄氧量以及4次1分钟、100%最大摄氧量）以及3天的休息/饮食控制。在耗尽运动后、力竭运动前和力竭运动后采集1%的外侧股四头肌肌肉活检样本，然后分析糖原含量。黄体中期（139.2 ± 14.9分钟）的力竭运动持续时间比卵泡中期（126 ± 17.5分钟）更长，存在强烈趋势（P < 0.07）。耗尽运动后的糖原补充（力竭运动前减去耗尽运动后）在黄体中期比卵泡中期更大（P = 0.05）（88.2 ± 4.7 vs 72.8 ± 5.7微摩尔/克湿重肌肉）。然而，力竭运动期间的糖原利用率（力竭运动前减去力竭运动后/力竭运动时间）在两个阶段之间没有差异（黄体中期 = 0.41 ± 0.08微摩尔/克湿重肌肉/分钟 vs 卵泡中期 = 0.33 ± 0.11微摩尔/克湿重肌肉/分钟；P = 0.17）。结果表明，月经周期的黄体中期运动表现和肌肉糖原含量会增强。这些发现意味着运动表现可能会受到月经周期阶段的影响。
