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Accurate and universal delineation of prokaryotic species.精确且通用的原核生物种系划分。
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Identification and characterization of microcin S, a new antibacterial peptide produced by probiotic Escherichia coli G3/10.鉴定和表征由益生菌大肠杆菌 G3/10 产生的新型抗菌肽微菌素 S。
PLoS One. 2012;7(3):e33351. doi: 10.1371/journal.pone.0033351. Epub 2012 Mar 30.
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Cryptic polyketide synthase genes in non-pathogenic Clostridium SPP.非病原性梭菌属(Clostridium SPP.)中的隐秘聚酮合酶基因
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Closthioamide: an unprecedented polythioamide antibiotic from the strictly anaerobic bacterium Clostridium cellulolyticum.氯硫酰胺:一种来自严格厌氧细菌解纤维素梭菌的前所未有的聚硫酰胺类抗生素。
Angew Chem Int Ed Engl. 2010 Mar 8;49(11):2011-3. doi: 10.1002/anie.200906114.
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Isolation and characterization of two members of the siderophore-microcin family, microcins M and H47.分离和鉴定两种铁载体-微菌素家族成员,微菌素 M 和 H47。
Antimicrob Agents Chemother. 2010 Jan;54(1):288-97. doi: 10.1128/AAC.00744-09. Epub 2009 Nov 2.
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Low-molecular-weight post-translationally modified microcins.低分子量翻译后修饰的微菌素
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从海洋沉积物中分离出的产抗菌物质的梭菌属菌株JC272的基因组序列草图

Draft Genome Sequence of Antimicrobial-Producing Clostridium sp. JC272, Isolated from Marine Sediment.

作者信息

Tushar L, Sasi Jyothsna T S, Sasikala C, Ramana C V

机构信息

Department of Plant Sciences, School of Life Sciences, University of Hyderabad, Hyderabad, India.

Centre for Environment, Bacterial Discovery Laboratory, Institute of Science and Technology, J. N. T. University Hyderabad, Hyderabad, India

出版信息

Genome Announc. 2015 Jun 11;3(3):e00650-15. doi: 10.1128/genomeA.00650-15.

DOI:10.1128/genomeA.00650-15
PMID:26067979
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4463543/
Abstract

We announce the draft genome sequence of Clostridium sp. JC272, isolated from a sediment sample collected from marine habitats of Gujarat, India. Clostridium sp. JC272 is an obligate anaerobe and has the ability to produce antimicrobial compounds. The genome sequence indicates the strain's capability of producing small peptides (microcins), which are potential novel antibiotics.

摘要

我们公布了从印度古吉拉特邦海洋栖息地采集的沉积物样本中分离出的梭菌属菌株JC272的基因组序列草图。梭菌属菌株JC272是一种专性厌氧菌,具有产生抗菌化合物的能力。基因组序列表明该菌株具有产生小肽(微菌素)的能力,这些小肽是潜在的新型抗生素。