Department of General Medicine, Diakonessenhuis, Utrecht, The Netherlands.
Department of Cardiology, Diakonessenhuis, Utrecht, The Netherlands.
Clin Kidney J. 2012 Feb;5(1):44-6. doi: 10.1093/ndtplus/sfr158. Epub 2012 Jan 28.
Little is known about the association between autosomal-dominant polycystic kidney disease (ADPKD) and coronary artery dissection (CAD). We suggest that the genetic disorder in ADPKD is the main cause of instable artery vasculature. Our case also shows that CAD can be missed in the acute phase. Therefore, we recommend additional investigation in patients with ADPKD presenting with acute chest pain. We report a case of a patient who developed a myocardial infarction due to a spontaneous dissection of the left anterior descending coronary artery. ADPKD was diagnosed during the additional investigation. The patient received medical management.
关于常染色体显性遗传性多囊肾病(ADPKD)与冠状动脉夹层(CAD)之间的关联知之甚少。我们认为,ADPKD 的遗传疾病是动脉血管不稳定的主要原因。我们的病例还表明,CAD 在急性期可能会被漏诊。因此,我们建议对出现急性胸痛的 ADPKD 患者进行额外的检查。我们报告了一例因左前降支冠状动脉自发性夹层导致心肌梗死的患者。在进一步检查中诊断出 ADPKD。患者接受了药物治疗。