Sodhi Kushaljit S, Krishna Satheesh, Saxena Akshay K, Sinha Anindita, Khandelwal Niranjan, Lee Edward Y
Departments of Radiodiagnosis and Imaging, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
Departments of Radiodiagnosis and Imaging, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
Eur J Radiol. 2015 Sep;84(9):1752-7. doi: 10.1016/j.ejrad.2015.05.030. Epub 2015 May 27.
Practice of ALARA (as low as reasonably achievable) principle in the developed world is currently well established. However, there is striking lack of published data regarding such experience in the developing countries. Therefore, the goal of this study is to prospectively evaluate CT request forms to assess how many children could be protected from harmful radiation exposure if 'Justification' and 'Optimization' principles of ALARA are applied before obtaining CT imaging in a developing country. This can save children from potential radiation risks including development of brain cancer and leukemia.
Consecutive CT request forms over a six month study period (May 16, 2013 to November 15, 2013) in a tertiary pediatric children's hospital in India were prospectively reviewed by two pediatric radiologists before obtaining CT imaging. First, 'Justification' of CT was evaluated and then 'Optimization' was applied for evaluation of appropriateness of the requested CT studies. The number (and percentage) of CT studies avoided by applying 'Justification' and 'Optimization' principle of ALARA were calculated. The difference in number of declined and optimized CT requests between CT requests from inpatient and outpatient departments was compared using Chi-Square test.
A total of 1302 consecutive CT request forms were received during the study period. Some of the request forms (n=86; 6.61%) had requests for more than one (multiple) anatomical regions, hence, a total of 1392 different anatomical CT requests were received. Based on evaluation of the CT request forms for 'Justification' and 'Optimization' principle of ALARA by pediatric radiology reviewers, 111 individual anatomic part CT requests from 105 pediatric patients were avoided. Therefore, 8.06% (105 out of 1302 pediatric patients) were protected from unnecessary or additional radiation exposure.The rates of declined or optimized CT requests from inpatient department was significantly higher than that from outpatient departments (p<0.05).
A substantial number of pediatric patients, particularly coming from outpatient departments, can be protected from unnecessary or additional radiation exposure from CT imaging when 'Justification' and 'Optimization' principle of ALARA are applied before obtaining CT imaging in a developing country.
在发达国家,“合理尽可能低(ALARA)”原则的实践目前已得到充分确立。然而,关于发展中国家此类经验的已发表数据却极为匮乏。因此,本研究的目标是前瞻性地评估CT申请单,以评估在一个发展中国家,若在进行CT成像前应用ALARA的“正当性”和“优化”原则,有多少儿童可免受有害辐射暴露。这可使儿童避免潜在的辐射风险,包括患脑癌和白血病。
在印度一家三级儿科儿童医院,两位儿科放射科医生在2013年5月16日至2013年11月15日这六个月的研究期间,对连续的CT申请单进行前瞻性审查,审查在进行CT成像之前。首先,评估CT的“正当性”,然后应用“优化”来评估所申请的CT检查的适宜性。计算通过应用ALARA的“正当性”和“优化”原则避免的CT检查的数量(及百分比)。使用卡方检验比较住院部和门诊部CT申请中被拒绝和优化的CT申请数量的差异。
在研究期间共收到1302份连续的CT申请单。一些申请单(n = 86;6.61%)要求对多个解剖区域进行检查,因此,共收到1392项不同的解剖部位CT申请。根据儿科放射科审查人员对CT申请单进行的ALARA“正当性”和“优化”原则评估,避免了来自105名儿科患者的111项个体解剖部位CT申请。因此,8.06%(1302名儿科患者中的105名)免受了不必要或额外的辐射暴露。住院部被拒绝或优化的CT申请率显著高于门诊部(p < 0.05)。
在发展中国家,在进行CT成像前应用ALARA的“正当性”和“优化”原则时,大量儿科患者,尤其是来自门诊部的患者,可免受CT成像带来的不必要或额外的辐射暴露。