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MultiElec：一款基于MATLAB的多电极阵列（MEA）数据分析应用程序。

MultiElec: A MATLAB Based Application for MEA Data Analysis.

作者信息

Georgiadis Vassilis, Stephanou Anastasis, Townsend Paul A, Jackson Thomas R

机构信息

Institute of Child Health, University College London, London, United Kingdom.

Institute of Cancer Sciences, University of Manchester, Manchester, United Kingdom; Manchester Centre for Cellular Metabolism, Manchester Cancer Research Centre, Faculty of Medical and Human Sciences, University of Manchester, Manchester, United Kingdom.

出版信息

PLoS One. 2015 Jun 15;10(6):e0129389. doi: 10.1371/journal.pone.0129389. eCollection 2015.

DOI:10.1371/journal.pone.0129389
PMID:26076010
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4468069/
Abstract

We present MultiElec, an open source MATLAB based application for data analysis of microelectrode array (MEA) recordings. MultiElec displays an extremely user-friendly graphic user interface (GUI) that allows the simultaneous display and analysis of voltage traces for 60 electrodes and includes functions for activation-time determination, the production of activation-time heat maps with activation time and isoline display. Furthermore, local conduction velocities are semi-automatically calculated along with their corresponding vector plots. MultiElec allows ad hoc signal suppression, enabling the user to easily and efficiently handle signal artefacts and for incomplete data sets to be analysed. Voltage traces and heat maps can be simply exported for figure production and presentation. In addition, our platform is able to produce 3D videos of signal progression over all 60 electrodes. Functions are controlled entirely by a single GUI with no need for command line input or any understanding of MATLAB code. MultiElec is open source under the terms of the GNU General Public License as published by the Free Software Foundation, version 3. Both the program and source code are available to download from http://www.cancer.manchester.ac.uk/MultiElec/.

摘要

我们展示了MultiElec，这是一个基于MATLAB的用于微电极阵列（MEA）记录数据分析的开源应用程序。MultiElec显示了一个极其用户友好的图形用户界面（GUI），它允许同时显示和分析60个电极的电压轨迹，并包括激活时间确定功能、带有激活时间的激活时间热图生成以及等值线显示功能。此外，还能半自动计算局部传导速度及其相应的矢量图。MultiElec允许临时信号抑制，使用户能够轻松有效地处理信号伪迹，并对不完整数据集进行分析。电压轨迹和热图可以简单导出以用于图形制作和展示。此外，我们的平台能够生成所有60个电极上信号进展的3D视频。功能完全由单个GUI控制，无需命令行输入或对MATLAB代码有任何了解。根据自由软件基金会发布的GNU通用公共许可证第3版的条款，MultiElec是开源的。程序和源代码均可从http://www.cancer.manchester.ac.uk/MultiElec/下载。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a8e/4468069/07df57ba06e3/pone.0129389.g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a8e/4468069/192024d03d5b/pone.0129389.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a8e/4468069/ec0946aab3df/pone.0129389.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a8e/4468069/11cd13c5d998/pone.0129389.g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a8e/4468069/46ab7a361837/pone.0129389.g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a8e/4468069/6a26a3619848/pone.0129389.g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a8e/4468069/1f0a63d5c5fd/pone.0129389.g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a8e/4468069/d53de0b12318/pone.0129389.g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a8e/4468069/63e68d0229ea/pone.0129389.g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a8e/4468069/07df57ba06e3/pone.0129389.g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a8e/4468069/192024d03d5b/pone.0129389.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a8e/4468069/ec0946aab3df/pone.0129389.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a8e/4468069/11cd13c5d998/pone.0129389.g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a8e/4468069/46ab7a361837/pone.0129389.g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a8e/4468069/6a26a3619848/pone.0129389.g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a8e/4468069/1f0a63d5c5fd/pone.0129389.g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a8e/4468069/d53de0b12318/pone.0129389.g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a8e/4468069/63e68d0229ea/pone.0129389.g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a8e/4468069/07df57ba06e3/pone.0129389.g009.jpg

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