开源无线电生理系统，用于在啮齿动物大脑中进行活体记录神经元活动。

An Open-Source Wireless Electrophysiological Complex for In Vivo Recording Neuronal Activity in the Rodent's Brain.

机构信息

Laboratory of Molecular Neurodegeneration, Graduate School of Biomedical Systems and Technologies, Institute of Biomedical Systems and Biotechnology, Peter the Great St. Petersburg Polytechnic University, 195251 Saint Petersburg, Russia.

National Technology Initiative Center for Advanced Manufacturing Technologies, Laboratory of Industrial Data Streaming Systems, Peter the Great St. Petersburg Polytechnic University, 195251 Saint Petersburg, Russia.

出版信息

Sensors (Basel). 2021 Oct 29;21(21):7189. doi: 10.3390/s21217189.

DOI:10.3390/s21217189

PMID:34770498

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8587815/

Abstract

Multi-electrode arrays (MEAs) are a widely used tool for recording neuronal activity both in vitro/ex vivo and in vivo experiments. In the last decade, researchers have increasingly used MEAs on rodents in vivo. To increase the availability and usability of MEAs, we have created an open-source wireless electrophysiological complex. The complex is scalable, recording the activity of neurons in the brain of rodents during their behavior. Schematic diagrams and a list of necessary components for the fabrication of a wireless electrophysiological complex, consisting of a base charging station and wireless wearable modules, are presented.

摘要

多电极阵列 (MEA) 是一种广泛用于记录体外/离体和体内实验中神经元活动的工具。在过去的十年中，研究人员越来越多地在体内实验中使用啮齿动物的 MEA。为了提高 MEA 的可用性和易用性，我们创建了一个开源的无线电生理系统。该系统是可扩展的，可以在啮齿动物的行为过程中记录其大脑中神经元的活动。本文呈现了一个无线电生理系统的原理图和所需组件列表，该系统由一个基础充电座和无线可穿戴模块组成。