Horváth O N, Jankásková J, Walker A, Sárdy M
Klinik und Poliklinik für Dermatologie und Allergologie, Ludwig-Maximilians-Universität, Frauenlobstr. 9-11, 80337, München, Deutschland.
Hautarzt. 2015 Aug;66(8):583-8. doi: 10.1007/s00105-015-3649-2.
The incidence and thereby also the relevance of pemphigoid diseases have significantly increased in elderly patients.
The clinical features, diagnostic workup, and therapy of pemphigoid diseases based on the recently published German guidelines and expert opinions are described.
The diagnosis is based on medical history, clinical manifestations, histopathology, and autoimmune serology. Treatment options depend on the diagnosis and disease severity. Both local and systemic immunosuppressive or immunomodulatory strategies have been proven to be effective.
Chronic, itchy, inflammatory skin disorders in elderly patients are generally suspicious for pemphigoid diseases. The prognosis is usually good. For decisions about (local or systemic) immunosuppressive therapy, gerontological aspects should be taken into consideration.
类天疱疮疾病在老年患者中的发病率及其相关性显著增加。
根据最近发布的德国指南和专家意见，描述类天疱疮疾病的临床特征、诊断检查和治疗方法。
诊断基于病史、临床表现、组织病理学和自身免疫血清学。治疗方案取决于诊断和疾病严重程度。局部和全身免疫抑制或免疫调节策略均已被证明有效。
老年患者的慢性、瘙痒性炎症性皮肤病一般怀疑为类天疱疮疾病。预后通常良好。在决定（局部或全身）免疫抑制治疗时，应考虑老年医学方面的因素。
