双侧丘脑底核脑深部电刺激术后帕金森病患者出现卡普格拉综合征：一例报告
Capgras Syndrome in a Patient with Parkinson's Disease after Bilateral Subthalamic Nucleus Deep Brain Stimulation: A Case Report.
作者信息
Kyrtsos Christina Rose, Stahl Mark C, Eslinger Paul, Subramanian Thyagarajan, Lucassen Elisabeth B
机构信息
College of Medicine, Penn State Milton S. Hershey Medical Center, Hershey, Pa., USA.
Department of Neurology, Penn State Milton S. Hershey Medical Center, Hershey, Pa., USA ; Department of Neural and Behavioral Sciences, Penn State Milton S. Hershey Medical Center, Hershey, Pa., USA.
出版信息
Case Rep Neurol. 2015 May 21;7(2):127-33. doi: 10.1159/000431081. eCollection 2015 May-Aug.
Capgras syndrome is a delusional misidentification syndrome (DMS) which can be seen in neurodegenerative diseases such as Lewy body dementia and, to a lesser extent, in Parkinson's disease (PD). Here, we report the case of a 78-year-old man with a history of idiopathic PD who developed Capgras syndrome following bilateral subthalamic nucleus deep brain stimulation (DBS) implantation. As the risk of DMS has been related to deficits in executive, memory, and visuospatial function preoperatively, this case highlights the importance of continuing to improve patient selection for DBS surgery. Capgras syndrome is a rare potential complication of DBS surgery in PD patients with preexisting cognitive decline.
卡普格拉综合征是一种妄想性错认综合征（DMS），可见于路易体痴呆等神经退行性疾病，在帕金森病（PD）中也有较少见的病例。在此，我们报告一例78岁男性患者，有特发性帕金森病病史，在双侧丘脑底核深部脑刺激（DBS）植入术后出现卡普格拉综合征。由于术前DMS的风险与执行、记忆和视觉空间功能缺陷有关，该病例凸显了持续改进DBS手术患者选择的重要性。卡普格拉综合征是DBS手术在已有认知功能减退的帕金森病患者中罕见的潜在并发症。
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