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与急性肺栓塞相关的游离右心血栓:一个尚未解决的治疗难题。

Free Floating Right Heart Thrombus Associated with Acute Pulmonary Embolism: An Unsettled Therapeutic Difficulty.

作者信息

Nkoke Clovis, Faucher Olivier, Camus Lise, Flork Laurence

机构信息

Department of Internal Medicine and Specialties, University of Yaounde 1, Yaounde, Cameroon ; Departement of Cardiology, Centre Hospitalier Guy Thomas, BP Box 167, 63204 Riom Cedex, France.

Departement of Cardiology, Centre Hospitalier Guy Thomas, BP Box 167, 63204 Riom Cedex, France.

出版信息

Case Rep Cardiol. 2015;2015:364780. doi: 10.1155/2015/364780. Epub 2015 May 11.

Abstract

Free floating right heart thrombus is a rare phenomenon in the context of acute pulmonary embolism and it is associated with a poor outcome. The increased use of echocardiography has led to an increased detection of right heart thrombi. However, optimal management of free floating right heart thrombus remains controversial with no clear consensus. We present the case of a 74-year-old woman who presented to the emergency department with acute onset dyspnea on minimal exertion which had developed over a period of 1 day. A computed tomography of the chest demonstrated massive bilateral proximal pulmonary embolism. A bedside transthoracic echocardiography performed showed a moderately dilated, poorly functioning right ventricle with visible highly mobile serpiginous thrombus moving to and fro across the tricuspid valve. Thrombolytic therapy was immediately initiated with tenecteplase which resulted in excellent results. Although there is no clear consensus for the management of right heart thrombus associated with pulmonary embolism, thrombolysis is readily available and can be effective in carefully selected patients.

摘要

在急性肺栓塞的情况下,游离性右心血栓是一种罕见现象,且与不良预后相关。超声心动图使用的增加导致右心血栓的检出率上升。然而,游离性右心血栓的最佳管理仍存在争议,尚无明确共识。我们报告一例74岁女性病例,该患者因在轻微活动时突发急性呼吸困难1天就诊于急诊科。胸部计算机断层扫描显示双侧近端大面积肺栓塞。床旁经胸超声心动图检查显示右心室中度扩张,功能不良,可见高度活动的蜿蜒状血栓在三尖瓣间来回移动。立即开始使用替奈普酶进行溶栓治疗,结果良好。尽管对于与肺栓塞相关的右心血栓的管理尚无明确共识,但溶栓治疗容易获得,并且在精心挑选的患者中可能有效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3577/4442267/6ff3e47e60c7/CRIC2015-364780.001.jpg

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