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≤50 岁行经皮冠状动脉介入治疗患者永久性工作残疾的预测因素。

Predictors of permanent work disability among ≤50-year-old patients undergoing percutaneous coronary intervention.

机构信息

Heart Center, Turku University Hospital, PO Box 52, 20521 Turku, Finland.

出版信息

Scand J Work Environ Health. 2015 Sep 1;41(5):460-6. doi: 10.5271/sjweh.3508. Epub 2015 Jun 17.

DOI:10.5271/sjweh.3508
PMID:26079321
Abstract

OBJECTIVES

This study aimed to describe the incidence and periprocedural predictors of permanent work disability (PWD) pension among patients ≤50 years old who underwent percutaneous coronary intervention (PCI).

METHODS

Patient records of 910 consecutive patients undergoing PCI at four Finnish hospitals in 2002-2012 were reviewed for baseline and procedural data and late adverse events. Data on permanent work disability (PWD) pension allocation were acquired from the Finnish Centre for Pensions, which governs the statutory pension security in Finland.

RESULTS

Mean follow-up was 41 [standard deviation (SD) 31] months. Altogether 103/910 (11.3%) of patients were on PWD by the end of follow-up, 60 (58.3%) for cardiac diagnoses (cumulative freedom from PWD 81% at 7 years). Independent predictors of PWD were post procedural stroke [hazard ratio (HR) 4.7, 95% confidence interval (95% CI) 1.8-11.9], post procedural myocardial infarction (MI) (HR 3.3, 95% CI 1.8-6.0), diabetes (HR 2.0, 95% CI 1.1-3.7), discharge diuretics (HR 3.5, 95% CI 2.1-5.9), and increasing age (HR 1.2, 95% CI 1.1-1.3). Predictors of PWD for cardiac diagnoses were post procedural stroke and MI, discharge diuretics, and use of calcium-channel blockers, diabetes and older age.

CONCLUSIONS

Patients ≤50 years old undergoing PCI are at a high risk for subsequent permanent disability for cardiac diagnoses. This finding underscores the need for reinforcing adherence to secondary prevention by cardiac rehabilitation and early collaboration with occupational health care professionals.

摘要

目的

本研究旨在描述在 2002 年至 2012 年期间于芬兰的 4 家医院接受经皮冠状动脉介入治疗(PCI)的≤50 岁患者中永久性工作残疾(PWD)抚恤金的发生率和围手术期预测因素。

方法

回顾了 910 例连续接受 PCI 的患者的病历,以获取基线和手术数据以及晚期不良事件数据。关于永久性工作残疾(PWD)抚恤金分配的数据来自芬兰养老金中心,该中心负责管理芬兰的法定养老金保障。

结果

平均随访时间为 41 个月(标准差 31 个月)。随访结束时,共有 103/910(11.3%)的患者领取了 PWD,其中 60 例(58.3%)患有心脏疾病(7 年时 PWD 无事件生存率为 81%)。PWD 的独立预测因素包括术后卒中(风险比[HR] 4.7,95%置信区间[95%CI] 1.8-11.9)、术后心肌梗死(MI)(HR 3.3,95%CI 1.8-6.0)、糖尿病(HR 2.0,95%CI 1.1-3.7)、出院时使用利尿剂(HR 3.5,95%CI 2.1-5.9)和年龄增加(HR 1.2,95%CI 1.1-1.3)。心脏疾病诊断的 PWD 预测因素包括术后卒中和 MI、出院时使用利尿剂、使用钙通道阻滞剂、糖尿病和年龄较大。

结论

接受 PCI 的≤50 岁患者患有心脏疾病的后续永久性残疾风险很高。这一发现强调了通过心脏康复和与职业健康护理专业人员的早期合作来加强二级预防的必要性。

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