Turk J Med Sci. 2015;45(2):416-30. doi: 10.3906/sag-1401-79.
Ankylosing spondylitis is a chronic, inflammatory, rheumatic disease that can reduce the quality of life and increase the risk of disability and mortality. It also causes direct and indirect economic losses due to health expenses and as a result of workforce loss. Management of this disease consists of pharmacological and nonpharmacological modalities. Until recently, pharmacological treatment options have been very limited. However, development of novel biological drugs revolutionized the management of this disease. The aim of this review article is to present an updated overview of the pharmacologic treatment of ankylosing spondylitis. Nonpharmacological treatment modalities including physiotherapy and exercise are only briefly mentioned and surgical treatment is not discussed.
强直性脊柱炎是一种慢性、炎症性、风湿性疾病，可降低生活质量，增加残疾和死亡风险。它还会因医疗费用和劳动力损失而造成直接和间接的经济损失。该病的治疗包括药物和非药物治疗方法。直到最近，药物治疗选择还非常有限。然而，新型生物药物的开发彻底改变了该病的治疗方法。本文旨在对强直性脊柱炎的药物治疗进行最新综述。非药物治疗方法（包括物理治疗和运动）仅简要提及，手术治疗不在讨论范围内。
