Scalapino K J, Davis J C
Division of Rheumatology, The University of California San Francisco, 533 Parnassus Avenue, Box 0633, Room U383, San Francisco, CA 94143, USA.
Clin Exp Med. 2003 Feb;2(4):159-65. doi: 10.1007/s102380300000.
Ankylosing spondylitis is an inflammatory disorder affecting the axial skeleton and periphery. Symptoms can often be debilitating. Current therapy for the disease include physical therapy, non-steroidal anti-inflammatory drugs (NSAIDS, anti-rheumatic disease modifying drugs (DMARDS), and the newly developed biologic agents targeting tumor necrosis factor alpha (TNF-alpha). This paper will provide a comprehensive review of these treatments which focusing on evidence based medicine for the daily clinical practice of rheumatology.
强直性脊柱炎是一种影响中轴骨骼和外周的炎性疾病。症状常常使人虚弱。该疾病目前的治疗方法包括物理治疗、非甾体抗炎药(NSAIDs)、抗风湿疾病改善病情药物(DMARDs)以及新研发的靶向肿瘤坏死因子α(TNF-α)的生物制剂。本文将对这些治疗方法进行全面综述,重点关注基于循证医学的风湿病日常临床实践。