青春期前男孩患巨大催乳素瘤并伴有溢乳
Massive prolactinoma with galactorrhoea in a prepubertal boy.
作者信息
Ross R J, McEniery J M, Grossman A, Doniach I, Besser G M, Savage M O
机构信息
Department of Endocrinology, St Bartholomew's Hospital, London, UK.
出版信息
Postgrad Med J. 1989 Jun;65(764):403-6. doi: 10.1136/pgmj.65.764.403.
Abstract
An 8 year old prepubertal boy presented with raised intracranial pressure, left proptosis and was noted to have galactorrhoea. Cranial computerized tomography revealed a large pituitary tumour infiltrating the cavernous sinus and left orbit. The serum prolactin was 180,600 mU/l (normal value less than 360 mU/l). Prolactinomas are rare in children and galactorrhoea has not previously been reported in a prepubertal child. The management of massive prolactinomas is difficult, but the child presented has made an impressive response to a combination of treatment with surgery, dopamine agonist therapy and radiotherapy.
摘要
一名8岁的青春期前男孩出现颅内压升高、左侧眼球突出，并被发现有溢乳现象。头颅计算机断层扫描显示一个巨大的垂体瘤，侵犯海绵窦和左侧眼眶。血清催乳素为180,600 mU/l（正常值小于360 mU/l）。催乳素瘤在儿童中罕见，青春期前儿童出现溢乳现象此前未见报道。巨大催乳素瘤的治疗困难，但该患儿经手术、多巴胺激动剂治疗和放疗联合治疗后反应良好。
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