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两亲性糖基聚原酸酯作为用于酸度增强型药物递送和细胞杀伤的pH响应性纳米组装体。

Amphiphilic sugar poly(orthoesters) as pH-responsive nanoscopic assemblies for acidity-enhanced drug delivery and cell killing.

作者信息

Li Lingyao, Knickelbein Kyle, Zhang Lin, Wang Jun, Obrinske Melissa, Ma Gene Zhengxin, Zhang Li-Ming, Bitterman Lindsay, Du Wenjun

机构信息

Department of Chemistry and Biochemistry, Science of Advanced Materials, Central Michigan University, Mount Pleasant, MI 48859, USA.

出版信息

Chem Commun (Camb). 2015 Aug 25;51(66):13078-81. doi: 10.1039/c5cc04078g.

DOI:10.1039/c5cc04078g
PMID:26096366
Abstract

A sugar poly(orthoester)-based drug delivery system was constructed to achieve acidity-enhanced drug delivery and cell killing.

摘要

构建了一种基于聚原酸酯糖的药物递送系统，以实现酸度增强的药物递送和细胞杀伤。

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Chem Commun (Camb). 2015 Aug 25;51(66):13078-81. doi: 10.1039/c5cc04078g.
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