Xu B M, Bi T X
Yao Xue Xue Bao. 1989;24(5):360-5.
This paper provides a new method to determine mixed component system by multiwavelength absorbance ratio difference spectrophotometry and summarized the basic principle and experimental technique of this method. This method was applied to assay the contents of two kinds of mixed component system of diphenhydramine hydrochloride and ephedrine hydrochloride, amidopyrine and caffeine without separation. The mean recoveries with coefficient of variation (%) was 101.0% (1.0%) for ephedrine hydrochloride; 94.86% (0.56%) for diphenhydramine hydrochloride; 100.3% (0.70%) for amidopyrine and 100.1% (0.75%) for caffeine. The results obtained are satisfactory both in recovery and in precision. It is a simple and rapid method to determine mixed component system.
本文提供了一种用多波长吸光度比值差分光光度法测定混合组分体系的新方法，并总结了该方法的基本原理和实验技术。该方法应用于不经分离测定盐酸苯海拉明和盐酸麻黄碱、氨基比林和咖啡因两种混合组分体系的含量。盐酸麻黄碱的平均回收率及变异系数（%）为101.0%（1.0%）；盐酸苯海拉明为94.86%（0.56%）；氨基比林为100.3%（0.70%）；咖啡因为100.1%（0.75%）。所得结果在回收率和精密度方面均令人满意。这是一种测定混合组分体系的简单快速的方法。
